Anti-Aging Products

Question 1

Chronological aging process. Affects the skin on the entire body. Slow, continuous, and irreversible tissue degradation

Answer 1

Intrinsic Aging

Question 2

Smooth, thin, pale, and finely-wrinkled. Thinning of dermis, degeneration of elastin (decrease elasticity), loss of hydration (dry skin), decrease immune cell function (slow healing of wounds)

Answer 2

Intrinsic Aging

Question 3

This is brought about by the reduction of collagen

Answer 3

Thinning of dermis

Question 4

Young skin: Wavy ; Aged skin: __________________

Answer 4

Flattened surface

Question 5

In intrinsic aging, barrier function of the skin is affected where ______ (drying/moisture) is observed, there is ________ (more/less) lipid content. In terms of melanocyte, there is _______ (more/less) density, there are _________ (more/less) blood vessels and (increased/reduced) vascular tissue, __________(hypertrophy/shrink) of sebaceous glands which results in the appearance of pores look (bigger/smaller)

Answer 5

drying; less; less; less; reduced; shrink; bigger

Question 6

Acceleration of intrinsic aging due to exposure to environmental factors

Answer 6

Extrinsic aging

Question 7

primary factors of extrinsic aging

Answer 7

UV radiation (photoaging) and smoking

Question 8

Affects skin of the face, neck, hands, and forearms. Coarse skin with wrinkles, hyperpigmented areas, sallowness, increased fragility, textural roughness, and telangiectasia

Answer 8

Extrinsic aging

Question 9

grayish-greenish yellow (paninilaw)

Answer 9

sallowness

Question 10

evident dilation of blood vessels

Answer 10

telangiectasia

Question 11

Naturally-sourced ingredients with multiple effects. Constituents depend on growing conditions, climate, weather, harvesting, and extraction methods. Used in very small amounts

Answer 11

Botanical extracts

Question 12

Protect cells from damage by neutralizing free radicals. May stimulate collagen production, preserve hyaluronic acid levels, and exert anti-inflammatory effects

Answer 12

Antioxidants

Question 13

Vitamin C, B3, and E; grapeseed extract, resveratrol, coenzyme Q10

Answer 13

Antioxidants

Question 14

Applied topically or as injectable. Has anti-inflammatory, wrinkle reduction, skin firming, smoothening, moisturizing, and protective effects

Answer 14

Peptides and proteins

Question 15

collagen, elastin, hydrolyzed wheat, soy protein, and botulinum toxin

Answer 15

Peptides and proteins

Question 16

Block the release of acetylcholine that would stop muscle contraction, preventing wrinkles. This is not permanent

Answer 16

Botulinum toxin

Question 17

Lipophilic molecules that can penetrate the epidermis and enter the dermis

Answer 17

retinoids

Question 18

retinoids improve surface roughness and age spots, reduce fine line by _______________________

Answer 18

decreasing collagen breakdown

Question 19

Can irritate the skin & cause photosensitization (this is an anti-aging active)

Answer 19

retinoids

Question 20

retinyl esters, retinol, retinaldehyde, retinoic acid

Answer 20

retinoids

Question 21

a retinoid that is prohibited in anti-aging product formulation. This is an OTC drug

Answer 21

retinoin

Question 22

Naturally-occurring organic carboxylic acids

Answer 22

Hydroxy acids

Question 23

Examples of alpha-hydroxy acids (AHAs)

Answer 23

lactic acid, glycolic acid, malic acid, tartaric acid, and citric acid

Question 24

Examples of beta-hydroxy acids

Answer 24

beta-hydroxybutyric acid and salicylic acids

Question 25

Example of polyhydroxy acids

Answer 25

gluconolactone

Question 26

Example of bionic acids

Answer 26

lactobionic acid

Question 27

Example of aromatic acids

Answer 27

salicylic acids

Question 28

Promote exfoliation, moisturization, anti-inflammatory, and anti-oxidative

Answer 28

Hydroxy acids

Question 29

(T/F) “Photosensitivity associated with the use of retinoids and AHAs is reversible”

Answer 29

True

Question 30

Surface desquamation. Reaches the epidermis only

Answer 30

Superficial peels

Question 31

Damage entire epidermis and upper dermis

Answer 31

medium-depth peels

Question 32

Wound the mid-dermis. Protein coagulation and complete peeling of epidermis with restructuring of basal layer and restoration of dermis.

Answer 32

deep peels

Question 33

Microscopic spherical vesicles with lipid bilayer structure. May be incorporated with hydrophilic and hydrophobic actives

Answer 33

liposomes

Question 34

Act as moisturizer. May shorten formulation shelf-life

Answer 34

liposomes

Question 35

In delivery systems, permeation is greater with _______________

Answer 35

liposomal encapsulation

Question 36

Eliminates irritation and optimizes dosage

Answer 36

liposomal encapsulation

Question 37

with liposomal encapsulation, there is __________ (greater/lower) concentration and residence time in the epidermis and dermis for ___________ (prolonged/shortened) release

Answer 37

greater; prolonged

Question 38

liposomal encapsulation protects the encapsulated materials from ______________

Answer 38

metabolic degradation

Question 39

Spherical vesicles made of nonionic surfactants. Accommodates active ingredients with wide range of solubility. No moisturizing effect. Have better oxidative stability than liposomes

Answer 39

niosomes

Question 40

Modified true or false: Solid Lipid Nanoparticles (SLN) are 2nd generation. Nanostructured Lipid Carriers are 1st generation.

Answer 40

Both false

Question 41

Usually contains one solid lipid. You can encapsulate the bioactive in the lipid matrix

Answer 41

SLN

Question 42

Limitation of SLN

Answer 42

Limitation on the drug actives you can incorporate

Question 43

The matrix consists of a blend of solid and liquid lipid. it allows flexibility in terms of ingredients that can be incorporated

Answer 43

NLC

Question 44

Provides light coverage, UV protection, hydration, and anti-aging benefits. Lighter than foundation but heavier than tinted moisturizer

Answer 44

Beauty Balm or Blemish Balm (BB)

Question 45

Address skin discoloration, dullness, or sallowness. Contain light-diffusing particles and antioxidants. Offer SPF protection

Answer 45

Color Correcting (CC)

Question 46

Combines benefits from BB and CC creams with primary focus on anti-aging. Help target appearance of wrinkles .

Answer 46

Daily Defense or Dynamic Do-All

Question 47

A delivery system that controls systemic absorption

Answer 47

Liposomes

Question 48

Bonus question: Who is the most beautiful person in the world? Clue: He is perfect and deserves himself but no one deserves him because his perfection belongs only to him

Answer 48

Andre Martin E. Marapao