Anti-inflammatory Cytokines Flashcards
(5 cards)
1
Q
What are the anti-inflammatory cytokines?
A
When i was 10, i watched TGiF-b and 1RA
IL10, TGF-b, IL1-RA
2
Q
What cells produce IL10?
A
Max BeaTREGby
M#, B-cells, Tregs
3
Q
What does secretion of IL10 lead to?
A
Inhibition of IL1b, IL6, IL8, IL12, TNF-a
Inhibits MHC II expression by APCs
Inhibits actions of activated T cells and TH1
4
Q
What cells produce TGF-b?
A
M#, Treg
5
Q
What does secretion of TGF-b lead to?
A
Inhibits 8 MaNKaB’s scars and heals their wounds Inhibits
Stimulates fibrosis/wound healing –> scars
proliferation and induces apoptosis in B cells and CD8+ cells
Inhibits M# and NKs
TH17 and Treg differentiation factor