Mediators Of Inflammation Flashcards by Marcus Thiemann

Q

The LPS from gram - bacteria triggers what two things?

A

Endothelial adhesion molecules

Cox-2

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Q

When uric acid crystals are engulfed by a macrophage, what cytokines are produced?

A

IL1 and IL8

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Q

What does IL1 signal after being secreted from Macrophages who ingest uric acid crystals?

A

Endothelial adhesion molecules

Cox-2

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Q

What is the physiologic outcome of Cox-2 activation?

A

Dilation and permeability increase in vessels

same results as Cox-1

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