Antihypertensive Drugs Flashcards

(34 cards)

1
Q

Alpha 1 blockers are

A

Prazocin and doxasosin

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2
Q

Combined alpha and beta blocker drug is

A

Labetalol

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3
Q

Adrenergic neuron blockers

A

Alpha methyldopa and reserpine

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4
Q

Vasodilators

A

Hydralazine

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5
Q

Central alpha 2 stimulants

A

Clonidine

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6
Q

Endothelin blockers

A

Bosentan

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7
Q

Dopamine agonist

A

Fenoldopam

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8
Q

ACEIs SH containing drugs …

A

Captopril

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9
Q

ACEIs non SH containing drugs…

A

Ramipril
Lisinopril
Benazepril

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10
Q

ARBs preparations….

A

Losartan
Olmesartan

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11
Q

Competitive inhibition of ANG2 at AT1 receptor

A

ARBs

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12
Q

ACE inhibitors side effects

A

CAPTOPRIL
cough
Angioedema
Proteinuria
Taste changes
Orthostatic hypotension
Pregnancy: teratogenicity
Rashes
Renal failure
Increased k+ due to decreasing of aldosterone
Leucopenia

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13
Q

Cautions of ACE inhibitors

A

Monitor serum of k+ and creatinine

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14
Q

Contraindications of ACE inhibitors

A

Pregnancy
Renal impairment
Dangerous hyperkalemia may occur with potassium sparing diuretics

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15
Q

From Beta blocker drugs and has VD action

A

Carvedilol

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16
Q

Cautions and contraindications of beta blockers

A

Variant angina
Asthma
Avoid abrupt withdrawal

17
Q

Drugs that are both myocardial depressants (inhibi conduction and contraction)

A

Verapamil
Beta blockers

18
Q

Calcium channel blockers

A

Verapamil
Nifedipine
Amlodipine
Diltiazem

19
Q

Relatively cardio selective
-Ve chronotropic and inotropic

20
Q

Smooth muscle selective
Potent arterial dilator

A

Nifedipine, amoldipine

21
Q

Intermediate properties

22
Q

Competitive inhibitors of catecholamines

A

Beta blockers

23
Q

Inhibit sympathetic Stimulation of heart

24
Q

Decrease renin release from kidney

A

Beta blockers

25
All of the following are side effects of Bradycardia Heart block Heart failure
Beta 1 effect
26
Bronchospasm Worsening PVD
Beta 2 effects
27
AV block Heart failure Constipation Are side effects of ...
Verapamil and diltiazem
28
Peripheral VD ( flushing, headache) Reflex tachycardia Ankle oedema Are side effects of....
Nifedipine and amoldipine
29
Drugs of first choice to treat patients with mild to moderate hypertension
Diuretics
30
Preparations of thiazide are ...
Hydrochlorothiazide Bendroflumethiazide
31
Drugs that lower BP by renal and extrarenal effects
Diuretics
32
Inhibition of NaCl reabsorption is
Renal effect
33
Direct VD action on resistance vessels Vascular response to pressor agents are reduced due to decrease Na content in vascular wall so PG(VD) will increase
Extrarenal effects
34
Side effects of diuretics 3hypo 4 hyper
Hypokalemia Hyponatremia Hypovolemia Hyperglycemia Hyperlipidemia Hyperuricemia Hypersensitivity