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KB - Psychiatry > Antipsychotics > Flashcards

Flashcards in Antipsychotics Deck (12):
1

What are some examples of typical antipsychotics?

haloperidol
chlorpromazine
thioridazine
fluphenazine

2

Are extrapyramidal side effects worse in typical or atypical antipsychotics?

typical

3

What are some side effects of antipsychotics?

sedation
weight gain
extrapyramidal symptoms and parkinsonism
prolonged QTc interval
increased prolactin

4

What are extrapyramidal symptoms?

parkinsonism
tardive dyskinesia
akathisia
acute dystonia

5

What is the mechanism of action of typical antipsychotics?

block dopamine 2 receptors

6

What are some examples of atypical antipsychotics?

rispiridone
olanzapine
quetiapine
clozapine - for resistant illness due to side effects
aripiprazole

7

What is the mechanism of action of atypical antipsychotics?

dopamine and 5HT antagonism

8

Which are worse for metabolic syndrome - typical or atypical?

atypical

9

Why do you monitor FBC with clozapine use?

risk of agranulocytosis

10

Why can't you use clozapine or olanzapine in pregnancy?

increased risk of gestational diabetes

11

What happens if someone misses their dose of clozapine for over 48 hours?

needs to be started again and titrated up slowly (start from the beginning)

12

What do antipsychotics increase the risk of in elderly patients?

stroke and VTE