Flashcards in Antipsychotics Deck (12):
What are some examples of typical antipsychotics?
Are extrapyramidal side effects worse in typical or atypical antipsychotics?
What are some side effects of antipsychotics?
extrapyramidal symptoms and parkinsonism
prolonged QTc interval
What are extrapyramidal symptoms?
What is the mechanism of action of typical antipsychotics?
block dopamine 2 receptors
What are some examples of atypical antipsychotics?
clozapine - for resistant illness due to side effects
What is the mechanism of action of atypical antipsychotics?
dopamine and 5HT antagonism
Which are worse for metabolic syndrome - typical or atypical?
Why do you monitor FBC with clozapine use?
risk of agranulocytosis
Why can't you use clozapine or olanzapine in pregnancy?
increased risk of gestational diabetes
What happens if someone misses their dose of clozapine for over 48 hours?
needs to be started again and titrated up slowly (start from the beginning)