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Flashcards in Bipolar Drugs Deck (12):
1

What mood stabiliser is first line in bipolar?

lithium

2

What can lithium cause?

nephrogenic diabetes insipidus

3

Is lithium safe in pregnancy?

No - can cause Ebstein's heart defect

4

What are the side effects of lithium?

dry mouth
strange taste
polydipsia and polyuria
hypothyroid
decreased renal function
weight gain

5

What are symptoms of lithium toxicity?

ataxia
tremor
N, V and D
drowsiness
convulsions, coma

6

Describe lithium monitoring.

prior to initiation - U and Es, ECG, TFTs
every 3 months - lithium level, U andEs
every 6 months - TFTs

7

What are some examples of anticonvulsants used in bipolar?

sodium valproate
lamotrigine
carbamazepine

8

What anticonvulsant is good in mania/hypomania?

valproate

9

What anticonvulsant is good in bipolar depression?

lamotrigine

10

Can lamotrigine be used in pregnancy?

No - cleft palate

11

What could a rash indicate with lamotrigine use?

Steven Johnsons sndrome

12

What are side effects of sodium valproate?

teratogenic
tremor
sedation
weight gain
dizziness
GI upset
pancreatitis