Flashcards in Antirrhythmic Drugs Deck (15):
What are types of antiarrhythmic drugs?
Class 1 Sodium channel blockers
Class 2 B adrenoceptor blockers
Class 3 Potassium channel blockers
Class 4 Calcium channel blockers
Class 5 Unclassified
What is MOA_antiarrhythmic_class 1 sodium channel blockers?
Decrease the rate of rise of phase 0 of the action potential by blocking sodium entry into the cell during deplorization
What are types of sodium channel blockers?
What are antiarrhythmic_class 1a_sodium channel blockers used for?
atrial and ventricular arrhythmias_all purpose antiarrhythmics
What is Procainamide (Pronestyl)?
Antiarrhythmic_sodium channel blocker_class 1a
Used for atrial, ventricular arrhythmias_all purpose
What are antiarrhythmic_sodium channel blocker_class 1b drugs used for?
used for treatment of ACUTE ventricular arrhythmias_ventricular tachycardia, ventricular fibrillation, and ventricular ectopy
What is Lidocaine (Zylocaine)?
Antirrhythmic_Sodium channel blocker_class 1b
What are antiarrhythmic sodium channel blocker class 1c drugs used for?
used for chronic suppression of ventricular arrhythmia
What is MOA_antiarrhythmic_class 2 drugs?
useful in suppressing the tacharrhythmia that resul from increase sympathetic activity by stabilizing cardiac membrane, slowing down conduction through SA and AV nodes, and increasing the refractory period
What is Propranolol(Inderal)?
antiarrhythmic_class 2_B-adrenoceptor blocker
most commonly used to treat arrhythmia patients
What is MOA_class 3_Potassium channel blockers?
Prolong repolarization; useful in treating intractable ventricular arrhythmias
What is Amiodarone?
antiarrhythmic drug_class 3_potassium channel blocker
effective in treatment and prevention of ventricular fibrillation and ventricular tachycardia
What is MOA_antiarrhythmic_class 4_calcium channel blockers?
Slow conduction and prolong the effective refractory period, especially in the AV node by blowing the inward calcium current
MOST EFFECTIVE against atrial than ventricular arrhythmias
What is Digoxin (Lanoxin)?
Antiarrhythmia_Unclassified class drug
used to control ventricular rate in atrial fibrillation or flutter