Applied Anatomy And Physiology (A2) Flashcards
(99 cards)
Define ATP
The energy currency of the body, and is the only usable form of energy for muscular contraction
What’s the structure of ATP
1 Adenosine
3 Triphosphate’s
Adenosine—P—P—P
Where’s ATP stored
In the muscle cell
What enzyme breaks ATP down
ATPase
What’s left when ATP is broken down
ADP + P + Energy
This is used for muscular contraction
What’s ADP
The compound formed when the terminal phosphate bond is removed from ATP
What’s exothermic mean
A reaction that gives out energy
E.g. breakdown of ATP used for muscular contraction
What’s an enzyme
A catalyst that speeds up the rate of a chemical reaction
How’s ATP resynthesised
Formula
Energy + ADP + P = ATP
How long can the body store ATP enough for
2-3 seconds of muscular contraction
Describe the ATP-PC system
- Type of reaction= Anaerobic
- Fuel used= Phosphocreatine
- Site of reaction= Sarcoplasm
- Controlling enzyme= Creatine Kinase
- ATP yield= 1:1
- By-products= No by-product
- Intensity of system= Very high intensity
- Duration of system= 2-10 seconds
- Individual and team examples= 100m and breaking line in rugby
Specific stages within the ATP-PC system
Look in book for enzyme
PC—> P + C + Energy (exothermic reaction)
Coupled reaction
Energy + ADP + P —> ATP
(endothermic reaction)
Evaluate the ATP-PC system
Advantages and disadvantages
Advantages:
- PC is readily available
- Anaerobic so don’t need to wait for oxygen to be available
- Simple and quick process
- No fatiguing by-products
Disadvantages:
- Limited stores of PC (only enough enough for up to 10 seconds of activity)
- Low ATP yield (1:1)
Describe the Glycolytic system (lactic acid system)
- Type of reaction= Anaerobic
- Fuel used= Glycogen/Glucose
- Site of reaction= Sarcoplasm
- Controlling enzyme= GPP, PFK, LDH
- ATP yield= 1:2 (2 ATP)
- By-products = Lactic acid
- Intensity system= High intensity
- Duration of system= 10-180 seconds
- Individual/team sport= 800m, long rally in tennis
Specific stages in the glycolytic system
Look in book for enzymes
Glycogen->Glucose->Pyruvic acid + energy
Coupled reaction
Energy + 2ADP + 2P—> 2ATP
Evaluate the Glycolytic system (lactic acid system)
Advantages: - Large supplies of glucose and glycogen available
- Anaerobic, so no need to wait for oxygen to be available
- Allows high intensity work for 3 mins
Disadvantages: - Build up of lactic acid as a by-product
- Low ATP yield (1:2)
- Recovery rate is slow (take up to 60 mins for lactate levels to return to resting values after strenuous activity
Describe the Aerobic system
-Type of reaction= Aerobic
-Fuel used= Glycogen/Glucose and fats
-Specific site of reaction=
Stage 1= Sarcoplasm
Stage 2= Mitochondria matrix
Stage 3= Mitochondria Cristae
-Controlling enzyme= GPP and PFK
-ATP yield=
Stage 1= 2 ATP
Stage 2= 2 ATP
Stage 3= 34 ATP
-By-products= CO2 and H2O
-Intensity of system= Low-moderate intensity/sub maximal
-Duration of system= 180 seconds onwards
-Individual/team sport examples= Football player lasting 90 mins, marathon runner
What are the 3 stages of the aerobic system
Stage 1= Aerobic glycolysis
Stage 2= Krebs cycle
Stage 3= ETC (Electron Transport Chain)
Specific stages within the aerobic system
Stage 1: aerobic glycolysis
Look in book for enzymes
Glycogen
Glucose
Pyruvic acid + Energy(2 ATP to resynthesise)
Acetyl CoA
Specific stages within the aerobic system
Stage 2: Kreb’s cycle
Acetyl CoA
Citric acid
Energy KREBS CYCLE. CO2
Hydrogen
Specific stages of the aerobic system
Stage 3: ETC (Electron Transport Chain)
Look in book for better diagram
Hydrogen
(Hydrogen ion) H+. e-(electron)
+
O2
|
H2O
34 ATP to resynthesise energy
Evaluate the aerobic system
Advantages and disadvantages
Advantages: - Large supplies of glucose, glycogen and fats available
- High ATP yield (1:38)
- No fatiguing by-products
Disadvantages: - Aerobic so have to wait for oxygen to be available
- Complex series of reactions
- Only work at submaximal intensity
- Takes long time to break down fats
Define fats (also called triglycerides)
Provides a good fuel for the aerobic system in the form of free fatty acids (FFA’s)
How does the aerobic system use fats as the fuel
1) The enzyme lipase speeds up the breakdown of triglycerides
2) To produce FFA’s and glycerol
3) FFA’s converted to Acetyl CoA
4) Acetyl CoA then continues through Kreb’s cycle and the ETC