Arterial Disorders

Question 1

inflammation of vessel wall

Answer 1

vasculitis

Question 2

presents as fever, malaise, GI issues, myalgia/arthralgia

Answer 2

vasculitis

Question 3

immune mediated and due to infections

Answer 3

vasculitis

Question 4

this is due to fibromuscular dysplasia

Answer 4

renal artery stenosis

Question 5

increased bp due to this; beaded appearance

Answer 5

renal artery stenosis

Question 6

vasculitis of aorta and branches of extremities, head and neck

Answer 6

large vessel

Question 7

vasculitis of visceral arteries and branches

Answer 7

medium vessel

Question 8

vasculitis of arterioles, venules, capillaries

Answer 8

small vessel

Question 9

giant cell (temporal) arteritis
Takayasu arteritis

Answer 9

large vessel vasculitis

Question 10

polyarteritis nodosa
Kawasaki disease

Answer 10

medium vessel vasculitis

Question 11

wegener granulomatosis
Churg-Strauss syndrome
Microscopic polyangiitis

Answer 11

small vessel vasculitis

Question 12

due to drug hypersensitivity or viral infection

Answer 12

immune complex deposition

Question 13

drug that forms immune complexes and deposit in large vessel

Answer 13

penicillin

Question 14

30% of patients w/ polyarteritis nodosa are ____

Answer 14

Hep B +

Question 15

autoantibodies directed against enzymes of neutrophils

Answer 15

ANCAs

Question 16

targeted antigen is PR3 of neutrophils; cytoplasmic

Answer 16

c-ANCA

Question 17

targeted MPO; perinuclear

Answer 17

p-ANCA

Question 18

Answer 18

c-ANCA

Question 19

Answer 19

p-ANCA

Question 20

most common large vessel vasculitis

Answer 20

Giant-Cell (Temporal) Arteritis

Question 21

granulomatous inflammation; facial pain, HA, painful chewing, diplopia/vision loss

Answer 21

Giant Cell (Temporal) Arteritis

Question 22

granulomatous vasculitis seen in women <40 yrs

Answer 22

Takayasu Arteritis

Question 23

reduced bp and weaker pulses in upper extremities; coldness/numbness in fingers

Answer 23

Takayasu arteritis

Question 24

“pulseless disease”

Answer 24

Takayasu arteritis

Question 25

segmental thrombosing of medium/small arteries (tibial and radial most common)

Answer 25

thromboangitis obliterans (Buerger Disease)

Question 26

young men, SMOKERS, claudication (Rx: cessation of smoking)

Answer 26

thromboangitis obliterans (Buerger Disease)

Question 27

Answer 27

thromboangitis obliterans (Buerger Disease)

Question 28

systemic vasculitis of medium/small arteries [ RENAL and VISCERAL vessels]

Answer 28

Polyarteritis Nodosa

Question 29

pulmonary circulation spared in this vasculitis

Answer 29

Polyarteritis Nodosa

Question 30

episodic intervals young adults renal/glomerular involvement

Answer 30

Polyarteritis Nodosa

Question 31

30% + for Hep B in this vasculitis

Answer 31

Polyarteritis Nodosa

Question 32

acute febrile, self limited illness infancy and childhood

Answer 32

Kawasaki Disease

Question 33

coronary artery involvement leads to ____% of MIs in Kawasaki Disease

Answer 33

20%

Question 34

presents w/ oral and conjunctival erythema; edema of hands and feet; enlarged lymph nodes (mucocutaneous lymph node syndrome)

Answer 34

Kawasaki Disease

Question 35

Answer 35

Kawasaki Disease

Question 36

necrotizing vasculitis all lesions same age necrotizing glomerulonephritis and pulmonary capillaries affected

Answer 36

Microscopic Polyangiitis

Question 37

KIDNEYS and LUNGS affected

Answer 37

Microscopic Polyangiitis

Question 38

p-ANCA in 70% of patients

Answer 38

Microscopic Polyangiitis

Question 39

Answer 39

Microscopic Polyangiitis

Question 40

necrotizing granulomas of upper resp. tract mainly (nasal cavity to alveoli); renal disease

Answer 40

Wegener Granulomatosis

Question 41

pneumonitis sinusitis mucosal ulceration renal disease

Answer 41

Wegener Granulomatosis

Question 42

c-ANCA in 95% of patients

Answer 42

Wegener Granulomatosis

Question 43

Answer 43

Wegener Granulomatosis

Question 44

necrotizing granulomas w/ eosinophils of LUNGs and HEART

Answer 44

Churg-Strauss Syndrome

Question 45

asthma increased eosinophils in blood numbness/pain in extremities lungs and heart

Answer 45

Churg-Strauss Syndrome

Question 46

most common vasculitis in children

Answer 46

Henoch-Schonlein Purpura

Question 47

presents as rash IgA immune complexes after Upper respiratory tract

Answer 47

Henoch-Schonlein Purpura

Question 48

endarteritis of vasa vasorum of proximal aorta

Answer 48

Syphilitic Aortitis

Question 49

accounts for 80% of tertiary disease

Answer 49

Syphilitic Aortitis

Question 50

scarring and can lead to aneurysm

Answer 50

Syphilitic Aortitis

Question 51

lumen of aorta; seen in what

Answer 51

Syphilitic Aortitis

Question 52

destruction of blood vessels due to fungi invasion

Answer 52

Aspergillus and Mucor Vasculitis

Question 53

seen in immunocompromised patients and diabetics

Answer 53

Aspergillus and Mucor Vasculitis

Question 54

autonomic issue that causes exaggerated response to cold and emotion; pallor or cyanosis to digits (hands/feets)

Answer 54

Raynaud Phenomenon

Question 55

abnormal connection b/t artery and vein; high output heart failure (due to decrease in bp)

Answer 55

Arteriovenous Fistula

Question 56

bulging veins blood clots due to either stasis in veins or turbulent flow in arteries

Answer 56

AV fistula

Question 57

heart failure and difficulty breathing due to

Answer 57

AV fistula

Question 58

blood flowing from the high pressure/ high flow artery into the low pressure/low flow vein causes what

Answer 58

causes bulging veins in AV fistula