Arterial Disorders Flashcards

1
Q

inflammation of vessel wall

A

vasculitis

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2
Q

presents as fever, malaise, GI issues, myalgia/arthralgia

A

vasculitis

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3
Q

immune mediated and due to infections

A

vasculitis

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4
Q

this is due to fibromuscular dysplasia

A

renal artery stenosis

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5
Q

increased bp due to this; beaded appearance

A

renal artery stenosis

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6
Q

vasculitis of aorta and branches of extremities, head and neck

A

large vessel

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7
Q

vasculitis of visceral arteries and branches

A

medium vessel

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8
Q

vasculitis of arterioles, venules, capillaries

A

small vessel

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9
Q

giant cell (temporal) arteritis
Takayasu arteritis

A

large vessel vasculitis

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10
Q

polyarteritis nodosa
Kawasaki disease

A

medium vessel vasculitis

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11
Q

wegener granulomatosis
Churg-Strauss syndrome
Microscopic polyangiitis

A

small vessel vasculitis

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12
Q

due to drug hypersensitivity or viral infection

A

immune complex deposition

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13
Q

drug that forms immune complexes and deposit in large vessel

A

penicillin

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14
Q

30% of patients w/ polyarteritis nodosa are ____

A

Hep B +

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15
Q

autoantibodies directed against enzymes of neutrophils

A

ANCAs

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16
Q

targeted antigen is PR3 of neutrophils; cytoplasmic

A

c-ANCA

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17
Q

targeted MPO; perinuclear

A

p-ANCA

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18
Q
A

c-ANCA

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19
Q
A

p-ANCA

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20
Q

most common large vessel vasculitis

A

Giant-Cell (Temporal) Arteritis

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21
Q

granulomatous inflammation; facial pain, HA, painful chewing, diplopia/vision loss

A

Giant Cell (Temporal) Arteritis

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22
Q

granulomatous vasculitis seen in women <40 yrs

A

Takayasu Arteritis

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23
Q

reduced bp and weaker pulses in upper extremities; coldness/numbness in fingers

A

Takayasu arteritis

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24
Q

“pulseless disease”

A

Takayasu arteritis

25
Q

segmental thrombosing of medium/small arteries (tibial and radial most common)

A

thromboangitis obliterans (Buerger Disease)

26
Q

young men, SMOKERS, claudication (Rx: cessation of smoking)

A

thromboangitis obliterans (Buerger Disease)

27
Q
A

thromboangitis obliterans (Buerger Disease)

28
Q

systemic vasculitis of medium/small arteries [ RENAL and VISCERAL vessels]

A

Polyarteritis Nodosa

29
Q

pulmonary circulation spared in this vasculitis

A

Polyarteritis Nodosa

30
Q

episodic intervals
young adults
renal/glomerular involvement

A

Polyarteritis Nodosa

31
Q

30% + for Hep B in this vasculitis

A

Polyarteritis Nodosa

32
Q

acute febrile, self limited illness
infancy and childhood

A

Kawasaki Disease

33
Q

coronary artery involvement leads to ____% of MIs in Kawasaki Disease

A

20%

34
Q

presents w/ oral and conjunctival erythema; edema of hands and feet; enlarged lymph nodes (mucocutaneous lymph node syndrome)

A

Kawasaki Disease

35
Q
A

Kawasaki Disease

36
Q

necrotizing vasculitis
all lesions same age
necrotizing glomerulonephritis and pulmonary capillaries affected

A

Microscopic Polyangiitis

37
Q

KIDNEYS and LUNGS affected

A

Microscopic Polyangiitis

38
Q

p-ANCA in 70% of patients

A

Microscopic Polyangiitis

39
Q
A

Microscopic Polyangiitis

40
Q

necrotizing granulomas of upper resp. tract mainly (nasal cavity to alveoli); renal disease

A

Wegener Granulomatosis

41
Q

pneumonitis
sinusitis
mucosal ulceration
renal disease

A

Wegener Granulomatosis

42
Q

c-ANCA in 95% of patients

A

Wegener Granulomatosis

43
Q
A

Wegener Granulomatosis

44
Q

necrotizing granulomas w/ eosinophils of LUNGs and HEART

A

Churg-Strauss Syndrome

45
Q

asthma
increased eosinophils in blood
numbness/pain in extremities
lungs and heart

A

Churg-Strauss Syndrome

46
Q

most common vasculitis in children

A

Henoch-Schonlein Purpura

47
Q

presents as rash
IgA immune complexes
after Upper respiratory tract

A

Henoch-Schonlein Purpura

48
Q

endarteritis of vasa vasorum of proximal aorta

A

Syphilitic Aortitis

49
Q

accounts for 80% of tertiary disease

A

Syphilitic Aortitis

50
Q

scarring and can lead to aneurysm

A

Syphilitic Aortitis

51
Q

lumen of aorta; seen in what

A

Syphilitic Aortitis

52
Q

destruction of blood vessels due to fungi invasion

A

Aspergillus and Mucor Vasculitis

53
Q

seen in immunocompromised patients and diabetics

A

Aspergillus and Mucor Vasculitis

54
Q

autonomic issue that causes exaggerated response to cold and emotion; pallor or cyanosis to digits (hands/feets)

A

Raynaud Phenomenon

55
Q

abnormal connection b/t artery and vein; high output heart failure (due to decrease in bp)

A

Arteriovenous Fistula

56
Q

bulging veins
blood clots due to either stasis in veins or turbulent flow in arteries

A

AV fistula

57
Q

heart failure and difficulty breathing due to

A

AV fistula

58
Q

blood flowing from the high pressure/ high flow artery into the low pressure/low flow vein causes what

A

causes bulging veins in AV fistula