Asthma Flashcards Preview

Clin Med I - Pulmonary > Asthma > Flashcards

Flashcards in Asthma Deck (22):
1

When is the peak age of presentation for asthma?

- 3 y/o

2

What is the strongest predisposing factor for developing asthma?

- atopy/allergic triad

3

What are principal allergens of asthma?

- dust mite
- animal dander
- cockroach
- grass & tree pollen
- alternaria (a soil mold)

4

What are the etiologies of asthma?

- hygiene hypothesis
- diet
- air pollution
- allergens
- occupational exposures

5

Describe the pathology of asthma

*REVERSIBLE*
- shedding of airway epithelium
- edema
- mucus plugging
- mast cell activation
- collagen deposition under the basement membrane

6

T/F: Over time, asthmatics incur permanent physiologic changes.

- True

7

Airflow is _______ proportionate to the ______ of the airway.

- inversely
- radius

8

What must be done to determine a definitive diagnosis of asthma?

- spirometry in pts older than 4

9

What are the symptoms of asthma?

- wheezing
- cough worse @ pm
- recurrent difficulty breathing
- chest tightness

10

T/F: A lack of wheezing and a normal chest exam do not exclude asthma.

- True

11

When do asthma symptoms occur or worsen?

- exercise
- inhalant allergens
- irritants
- changes in weather
- strong emotional response
- stress
- menstrual cycles

12

What are signs of severe asthma?

- hypoxemia
- hypercapnia
- pulsus paradoxus

13

T/F: CXR is always indicated in asthma r/o

- False, not routinely indicated

14

What is the hallmark of asthma?

- bronchial hyper-responsiveness

15

What are tests that can be done for an asthma dx?

- methocholine challenge
- spirometry
- labs

16

Describe spirometry values for an obstructive dz

- FVC normal or decreased
- FEV1 decreased by < 80%
- FEV1/FVC decreased by <70%

17

Describe spirometry values for a restrictive dx

- FVC decreased by <80%
- FEV1 decreased
- FEV1/FVC normal

18

When is stridor heard, inspiration or expiration? wheeze?

- stridor = inspiration
- wheeze = expiration

19

What is the goal of asthma therapy?

- reduce impairment
- reduce risk

20

What is the stepwise management of asthma?

- SABA
- LABA
- ICS
- LTR
- cromolyn
- theophylline
- oral steroid
- zileuton
- omalizumab

21

What are adrenergic beta-agonists?

- rescue inhalers

22

What is the effect of adrenergic beta-agonists on airways?

- relaxation of airway smooth m.
- increase mucocilliary clearance & mucus secretion
- decrease cough
- no effect on chronic inflam