Lung Cancer Flashcards Preview

Clin Med I - Pulmonary > Lung Cancer > Flashcards

Flashcards in Lung Cancer Deck (40)
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1
Q

_____ ______ is etiologic in ~85% of cases

A
  • cigarette smoking
2
Q

What is lung CA risk related to?

A
  • pack years
3
Q

What is the best treatment for lung CA?

A
  • prevention
4
Q

Nicotine produces _______, stopping produces ______.

A
  • tolerance

- withdrawal

5
Q

T/F: The majority of patients dx’d w/ lung CA, die of their disease.

A
  • True
6
Q

What are the most frequent presenting symptoms of lung CA?

A
  • cough
  • wt loss
  • dyspnea
  • chest pain
  • hemoptysis
7
Q

What will be found on physical exam in lung CA?

A
  • asymmetric breath sounds
  • basilar dullness
  • lymphadenopathy
  • organomegaly
  • bone tenderness
  • unexplained neuro sx
8
Q

What lab tests should be ordered in lung CA?

A
  • CBC
  • chem profile
  • PT & APTT
9
Q

What images should be ordered in lung CA?

A
  • CXR
  • chest w/ or w/o abdomen CT
  • brain MRI as indicated by S&S
10
Q

T/F: Treatment should be started before biopsy.

A
  • False!

- no meat, no treat

11
Q

What are the two categories of epithelial lung CA?

A
  • small cell (SCLCa)

- non small cell (NSCLCa)

12
Q

Define limited stage lung CA

A
  • limited to 1 side of the chest
13
Q

Define extensive stage lung CA

A
  • beyond 1 side of the chest
14
Q

Define Stage 1A lung CA

A
  • ≤ 3cm, N0
15
Q

Define Stage 1B lung CA

A
  • > 3cm ≤ 5cm, N0
16
Q

Define Stage 2A lung CA

A
  • ≤ 5cm, N1

- < 5cm ≤ 7cm, N0

17
Q

Define Stage 2B lung CA

A
  • > 5cm ≤ 7cm, N1
  • proximal tumor
  • invades thorax, N0
18
Q

Define Stage 3A lung CA

A
  • mediastinal LNs (+)
19
Q

Define Stage 3B lung CA

A
  • non-resecatble
20
Q

Define Stage 4 lung CA

A
  • metastatic
21
Q

What is the tx for Stage 1A lung CA?

A
  • surgery alone
22
Q

What is the tx for Stage 1B lung CA?

A
  • surgery +/- chemo
23
Q

What is the tx for Stage 2A&B lung CA?

A
  • surgery +/- chemo
24
Q

What is the tx for Stage 3, T3N1 lung CA?

A
  • surgery +/- chemo
25
Q

What is the tx for Stage 3, N2 or N3, and 3A lung CA?

A
  • combo chemo & radiation
26
Q

What is the tx for Stage 3B or 4 lung CA?

A
  • palliative chemo

- symptomatic radiation

27
Q

What is the tx for limited Stage lung CA?

A
  • combo chemo & radiation
28
Q

What is the tx for extensive Stage lung CA?

A
  • palliative chemo

- symptomatic radiation

29
Q

What other condition is not uncommon in patients with bone metastases or paraneoplastic syndrome?

A
  • hypercalcemia
30
Q

What other disease is occasionally associated with SCLCa?

A
  • Cushing’s Syndrome

- Lambert-Eaton Syndrome

31
Q

What other condition is not uncommon in SCLCa or NSCLCa?

A
  • SIADH (syndrome of inappropriate ADH secretion)
32
Q

What is common in SCLCa and adenoCA of lung?

A
  • brain metastases
33
Q

What is a disease almost exclusively a result of asbestos exposure?

A
  • mesothelioma
34
Q

What is the mainstay of curative tx for NSCLCa?

A
  • surgery
35
Q

What is the only tx for SCLCa?

A
  • chemo +/- radiation
36
Q

What is a NCOG Performance Status of 0?

A
  • no disability

- normal ADLs

37
Q

What is a NCOG Performance Status of 1?

A
  • minor disability
  • light work
  • no strenuous work
38
Q

What is a NCOG Performance Status of 2?

A
  • moderate disability
  • no work
  • can care for self
  • in bed some part of waking day
39
Q

What is a NCOG Performance Status of 3?

A
  • in bed most of day

- some self care

40
Q

What is a NCOG Performance Status of 4?

A
  • in bed all the time

- no self care