Pleural Diseases Flashcards

(57 cards)

1
Q

Describe the normal physiology of the pleural space

A
  • fluid enters from capillaries in the visceral pleura

- fluid absorbed via lymphatics in the parietal pleura

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2
Q

Define pleural effusion

A
  • abnormal build up of fluid in the pleural space
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3
Q

What can cause a pleural effusion?

A
  • pleural fluid formation > absorption
  • rate of absorption is decreased
  • transport of peritoneal fluid from the abdominal cavity through the diaphragm or via lymphatics from a subdiaphragmatic process
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4
Q

Describe the physiology of pleural effusion and the result of each

A
  • increased production of fluid in normal capillaries (abnormal pressure changes) ==> low protein “transudates”
  • increased production of fluid d/t abnormal capillary permeability/inflam ==> high-protein “exudates”
  • decreased lymphatic clearance ==> high protein “exudates”
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5
Q

Define empyema

A
  • infection in pleural space
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6
Q

Define hemothorax

A
  • bleeding into the pleural space
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7
Q

Define chylothroax

A
  • lymphatic leakage from the thoracic duct or one of the main lymphatic vessels that drains into it
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8
Q

What are the types of pleural effusions?

A
  • transudative
  • exudative
  • pus
  • blood
  • chyle
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9
Q

When do transudative type pleural effusion occur?

A
  • altered systemic factors
  • absence of local pleural disease
  • leakage of fluid from intact normal capillaries d/t increased hydrostatic or decreased oncotic pressures
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10
Q

What are the causes of pleural effusion?

A
  • MC: CHF
  • nephrotic syndrome
  • atelectasis
  • chirrhosis
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11
Q

When do exudative pleural effusions occur?

A
  • altered local factors
  • presence of pleural disease
  • increased production by the capillaries or blocking of lymphatics
  • impaired lymphatic drainage/leaky capillaries
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12
Q

What are the causes of exudative pleural effusions?

A
  • MC: parpneumonic effusion
  • 2nd MC: 2ndary to malignancy
  • mesothelioma
  • PE
  • trauma
  • 2ndary to viral infection
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13
Q

What are the 3 types of parapneumonic pleural effusions?

A
  • simple/uncomplicated
  • complicated
  • empyema
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14
Q

What causes hemothorax?

A
  • MC: trauma
  • surgery
  • tumor
  • ruptured blood vessel
  • spontaneous
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15
Q

What is diagnostic of hemothorax?

A
  • pleural fluid hematocrit:peripheral blood hematocrit > 0.5
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16
Q

What causes chylothorax?

A
  • MC: lymphoma & surgical trauma
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17
Q

What does the cylothorax fluid look like?

A
  • milky, white
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18
Q

What are the symptoms of pleural effusion?

A
  • dyspnea
  • pleuritic chest pain
  • cough
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19
Q

What are the signs of pleural effusion?

A
  • hypoxic
  • decreased unilateral chest movement on affected side
  • decreased breath sounds over area
  • dull to percussion
  • decreased tactile fremitus
  • pleural friction rub
  • tracheal deviation to contalateral side if large
  • egophony
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20
Q

What does a pleural friction rub indicate?

A
  • infarction

- pleuritis

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21
Q

What diagnostic tests are ordered for pleural effusion?

A
  • CXR

- CT

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22
Q

What amount of fluid is required to see pleural effusion

A
  • 75-100mL on lateral view

- 175-200mL on AP/PA view

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23
Q

How is a lateral decubitus CXR view helpful for pleural effusion?

A
  • identifies free flowing vs. loculated effusions
24
Q

What is the treatment of pleural effusion?

A
  • thoracentesis

- tx underlying dz

25
What would purulent fluid from a thoracenteis point towards?
- empyema
26
What would putrid odor from a thoracenteis point towards?
- anaerobic empyema
27
What would milky, white fluid from a thoracenteis point towards?
- chylothorax
28
What would blood from a thoracenteis point towards?
- trauma | - malignancy
29
What is the traditional method to ddx between exudative and trasudative pleural effusions?
- Lights Criteria
30
What would the Lights Criteria yield in exudative pleural effusion?
- meets at least 1 criteria
31
What would the Lights Criteria yield in transudative pleural effusion?
- meets no criteria
32
What is the treatment for malignant effusion?
- pleurodesis | - serial thoracentesis if recurs
33
What is the treatment for empyemas?
- drainage | - long term abx
34
What is the treatment for hemothorax?
- immediate large bore chest tube placement
35
What is the definition of pleuritis/pleurisy?
- pain d/t acute pleural inflam caused by iritation of the parietal pleura
36
What causes pleuritis/pleurisy?
- anything that causes inflam
37
What are S&S of pleuritis/pleurisy?
- sharp, localized chest pain | - worsened by sneezing, deep breathing, or movement
38
What is the treatment for pleuritis/pleurisy?
- tx underlying dz - anti-inflam - pain control
39
Define pneumothorax
- collection of gas/air in the pleural space ==> collapsed lung
40
What are the types of Ptx?
- primary spontaneous - secondary spontaneous - traumatic - iatrogenic - tension
41
What causes a primary spontaneous Ptx?
- absence of underlying lung dz
42
What causes a secondary spontaneous Ptx?
- presence of underlying lung dz
43
What causes a traumatic Ptx?
- penetrating or blunt trauma | - open wound
44
What causes iatrogenic Ptx?
- s/p procedures
45
What causes tension Ptx?
- trauma - lung infections - mechanical ventilation - resucitative efforts
46
What patient population is at highest risk for primary spontaneous Ptx?
- tall, thin, males 10-30 y/o
47
What is the suspected etiology of primary spontaneous Ptx?
- rupture of a subpleural apical bleb
48
For _______ Ptx, air pressure in the _______ _______ exceeds _______ pressure throughout the respiratory cycle
- tension - pleural space - ambient
49
What happen to the internal chest organs in tension Ptx?
- pushed to contralateral side
50
What are two events that occur with tension Ptx?
- hypoxia | - CV system collapse
51
What are the S&S of all types of Ptxs?
- chest pain on affected side - dyspnea - anxiety - fatigue - acute epigastric pain
52
What is seen on PE for Ptx?
- respiratory distress - tachycardia - unilateral chest expansion - decreased breath sounds on affected side - decreased tactile fremitus - hyperressonace
53
Which of the common PE findings for Ptx suggest tension Ptx?
- tachycardia - hypotension - mediastinal/trachial shift
54
What tests should be ordered for Ptx?
- CXR - ABG - EKG - CT - US
55
What will be seen on CXR for Ptx?
- ipsilateral lung edge/visceral pleural line parallel to chest wall - increased lucency - deep sulcus sign
56
What is the tx for Ptx?
- small ( observation - supplemental O2 to increase rate of reabsorption - chest tube - immediate decompression for tension
57
How can Ptxs be prevented in patients w/ (+) hx of Ptx?
- surgical removal of blebs or broncho-pleural fistulas - smoking cessation - minimize high altitude flying - avoid SCUBA diving