Hyaline Membrane Disease Flashcards Preview

Clin Med I - Pulmonary > Hyaline Membrane Disease > Flashcards

Flashcards in Hyaline Membrane Disease Deck (15):
1

What is another name for hyaline membrane disease?

- respiratory distress syndrome

2

What is the patient age group that hyaline membrane disease almost exclusivly effects?

- premature infants

3

What is the relationship between gestational age and incidence/severity of hyaline membrane disease?

- inversely related
i.e. younger kids are worse

4

What is the epidemiology of hyaline membrane disease?

- preterm infant

5

What are the risk factors of hyaline membrane disease?

- siblings with RDS
- diabetic mother
- c-section
- multiple pregnancies
- rapid labor
- delivery complications with decreased blood flow to baby

6

What is the pathophysiology of hyaline membrane disease?

- surfactant deficiency

7

What is the function of surfactant?

- decreases surface tension in alveoli to remain partially expanded.

8

What occurs in the absence of surfactant?

- poor lung compliance
- atelectasis
- infant must expend a lot of energy to expand the lung

9

What are the symptoms of hyaline membrane disease?

- onset w/in minutes of birth or may not be seen for several hrs
- tachypnea, apnea, hypopnea
- cyanosis
- decreased urine output
- SOB & grunting
- nasal flaring
- drawing back chest muscles

10

What will be seen on CXR in hyaline membrane disease?

- atelectasis
- ground glass appearance
- air bronchograms
- low lung volumes

11

What diagnostic tests should be ordered for hyaline membrane disease?

- CXR
- CBC
- blood gas
- Echo

12

What is the treatment for hyaline membrane disease?

- humidified O2
- nasal CPAP
- early intubation prn
- artificial surfactant replacement therapy

13

What can be given to the mother prior to delivery of a fetus with hyaline membrane disease?

- steroids

14

Describe the dosing schedule for Rescue Surfactant

- 1st dose ASAP after birth (less effective as dz progresses)
2nd dose given to infants on ventilation and more than 30-40% FIO2

15

How can hyaline membrane disease be prevented?

- prevent premature births
- avoid poorly timed & unnecessary C-sections
- halt labor until lungs mature
- steroids prior to delivery