Autonomic Nervous System Flashcards

(43 cards)

1
Q

What are 2 anatomical components of the PNS?

A

ganglia and nerves

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2
Q

What are the 2 divisions of the afferent part of the PNS?

A
  • Somatosensory
  • Special sensory
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3
Q

Which division of the motor aspect of the PNS regulates blood vessels, glands and organs?

A

Autonomic or visceral?

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4
Q

Sympathetic is _______________(catabolic/anabolic)

A

Catabolic (increases contraction)

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5
Q

Where are the cell bodies located in the spinal cord?

A

Intermediolateral grey column

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6
Q

The anabolic ANS is described as ____________.

A

Parasympathetic

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7
Q

Which flow is in the sympathetic ANS?

A

Thoracolumbar flow

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8
Q

The craniosacral flow involves which cranial and sacral nerves?

A

Cranial: X (vagus)
Sacral: pelvic

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9
Q

Which neurotransmitter is in the parasympathetic ANS?

A

ACh

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10
Q

NE/E is part of which ANS division?

A

Sympathethic

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11
Q

What is the relay station outside of CNS?

A

A ganglion

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12
Q

Which axons are longer in the sympathetic ANS? (Pre/Post)

A

Post-ganglionic

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13
Q

Which axons release ACh in the sympathetic ANS?

A

Pre-ganglionic

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14
Q

What are the catecholamines?

A

Epinephrine and Norepinephrine

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15
Q

List the neurotransmitter released by pre and the post ganglionic axons in the parasympathetic NS

A

Both release ACh

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16
Q

Define the limits of the vagosympathetic trunk

A

C1-C4

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17
Q

What CN are involved in the craniosacral flow of the vagosympathetic trunk?

A

CN 3, 7, 9, 10

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18
Q

What CN are involved in the craniosacral flow of the vagosympathetic trunk?

A

CN 3, 7, 9, 10

19
Q

List the 3 structures involved in the sympathetic NS ?

A
  • vertebral n
  • hypogastric n
  • pelvic plexus
20
Q

What is the type of response that ACh is related to?

A

Cholinergenic

21
Q

What is the enzyme that breaks down ACh and where does it do it?

A

Acetylcholinesterase (AChE) at the synaptic cleft

22
Q

List the 2 receptors that bind ACh

A
  • Nicotinic
  • Muscarinic
23
Q

Describe the Nicotinic receptor (type, locations)

A
  • somatic and ionotropic
  • muscles in the NMJ
24
Q

Which ACh receptor is autonomic, metabotropic and innervates glands?

25
Which Muscarinic receptor is in sweat /salivary glands?
M1
26
ACh M2 Receptor is located in __________
The heart
27
Which M ACh receptor is in the sphincters and GIT?
M3
28
What are 2 ways that one can regulate the activity of ACh?
- Clear AChE - Internalize the cholinergenic receptors
29
List 3 types of substances that can target the cholinergenic receptor
- agonist - antagonist - Synergistic (assists activation)
30
Neostigme is an example of and what does it treat
AChE inhibitor - muscle strengthener Tx for myasthenia gravis
31
What can block ACh release that causes flaccid paralysis?
Botulinum toxins
32
What can Turbocurarine do ?
Block NMJ receptors (myorelaxant)
33
Give an example of a Muscarinic receptor antagonist
Atropine
34
What can atropine treat?
Glaucoma
35
What are the 3 receptor types that Norepinephrine ?
- alpha - 1 - alpha -2 - Beta
36
What type of receptor are the NE ?
GCPR
37
Are NE receptors post or pre ganglionic?
Post
38
Are NE receptors post or pre ganglionic?
Post
39
Is NE short or half life?
Long Half life
40
Is epinephrine short or long half life?
Short
41
What are the 2 enzymes that break down monoamine oxidase?
- Monoamine oxidase (MOA) - Catechol-O-methyl transferase
42
Which NE enzyme is located in the synaptic cleft?
MAO
43
Where is COMT (NE enzyme) located?
Pre - synaptic ganglion (axons)