B Cells - week 4 PBL

Question 1

Where do B cells originate from?

Answer 1

Bone marrow

Question 2

Function of B cells?

Answer 2

Identify foreign antigens

B cell processes and presents antigen on surface
Helper T cell binds to antigen
T cell secrete lymphokines and B cells divide into Plasma cells (antibody production) or B memory cells

Question 3

What immunoglobulin is first secreted when vaccine antigen is presented to the body ?

Answer 3

IgM - innate immune system

Question 4

After 11 days of vaccine antigen introduction what immunoglobulins are produced?

Answer 4

IgG - adaptive immune system

Question 5

What happens to immune response when the same antigen is introduced again?

Answer 5

Much more rapid response
Mainly IgG antibodies
Slower decline in antibody production

Question 6

Role of IgG, IgE, IgA?

Answer 6

IgG: in blood supply, circulating, attaching to pathogens
IgE: getting rid of parasites on skin and mucosal surfaces. Relates to MAST and eosinophil cells
IgA: secreted across mucosal surfaces to pick up pathogens before they enter the body