B4-069 Cardiomyopathies

Question 1

most common cardiomyopathy

Answer 1

dilated

Question 2

leads to systolic dysfunction

Answer 2

dilated

Question 3

familial dilated cardiomyopathy is caused by a mutation in what protein?

Answer 3

titin

Question 4

heart failure
S3 sound
sytolic regurgitant murmur

Answer 4

dilated cardiomyopathy

Question 5

balloon appearance of heart on CXR

Answer 5

dilated cardiomyopathy

Question 6

caused by mutations in myosin binding protein C and beta myosin heavy chains

Answer 6

hypertrophic cardiomyopathy

Question 7

causes syncope during exercise, may lead to SCD

Answer 7

hypertrophic cardiomyopathy

Question 8

S4 sound
systolic murmur
maybe mitral regurg

Answer 8

hypertrophic cardiomyopathy

Question 9

cause diastolic dysfunction

2

Answer 9

hypertrophic cardiomyopathy
retrictive cardiomyopathy

Question 10

eccentric hypertrophy

Answer 10

dilated cardiomyopathy

Question 11

concentric hypertrophy
septal predominance

Answer 11

hypertrophic cardiomyopathy

Question 12

most common genetic heart disease
most frequent cause of sudden cardiac death in young people

Answer 12

hypertrophic

Question 13

• globoid
• markedly enlarged

Answer 13

dilated cardiomyopathy

Question 14

strong alcohol use association

Answer 14

dilated cardiomyopathy

Question 15

excess catecholamines
pheochromocytoma

Answer 15

dilated cardiomyopathy

Question 16

subendocardial scars
mural thrombi

Answer 16

dilated cardiomyopathy

Question 17

ejection fraction less than 25%

Answer 17

dilated cardiomyopathy

Question 18

massive myocardial hypertrophy without ventricular dilation

Answer 18

hypertrophic cardiomyopathy

Question 19

massive myocyte hypertrophy
haphazard disarray of bundles of myocytes

Answer 19

hypertrophic cardiomyopathy

Question 20

cavities are not dilated
myocardium largely unremarkable

Answer 20

restrictive cardiomyopathy

Question 21

name that restrictive cardiomyopathy

• children and YA
• linked to nutritional deficiencies and parasitic infections
• most common form worldwide

Answer 21

endomyocardial fibrosis

Question 22

name that restrictive cardiomyopathy

• large mural thrombi
• peripheral eosinophilia
• associated with PDGFR

Answer 22

loeffler endomyocarditis

Question 23

• fibroelastic thickening involving LV
• most common in first 2 years of life
• genetic

Answer 23

endocardial fibroelastosis

Question 24

non-caseating, non-necrotizing granulomas

Answer 24

sarcoidosis

restrictive

Question 25

* autosomal disorder * causes right sided HF and rhythm disturbances * massive fatty infiltration and focal fibrosis

Answer 25

arrhythmogenic cardiomyopathy

Question 26

most common viral causes of myocarditis in US

Answer 26

* coxsackie * CMV * HIV * influenza

Question 27

non viral causes of myocarditis

Answer 27

* T. cruzi * Trichinosis * Toxoplasmosis * Lyme * Diptheria

Question 28

* interstitial inflammatory infiltrate * diffuse, mononuclear lymphocytic infiltrate

Answer 28

myocarditis

Question 29

hypersensitivity myocarditis is characterized by what pathologic finding?

Answer 29

eosinophils

Question 30

associated with pregnancy

Answer 30

dilated cardiomyopathy

Question 31

what inheritance pattern is associated with HCM

Answer 31

autosomal dominant

Question 32

stiff, non compliant myocardium

Answer 32

restrictive cardiomyopathy

Question 33

amyloidosis causes what kind of cardiomyopathy?

Answer 33

restrictive

Question 34

increased interstitial fibrosis due to radiation causes

Answer 34

restrictive cardiomyopathy

Question 35

cobalts anthracyclines cocaine cyclophosphamide | are associated with

Answer 35

dilated cardiomyopathy

Question 36

ejection fraction between 50-80%

Answer 36

hypertrophic cardiomyopathy

Question 37

* fatal condition * multiple non-caseating granulomas * multinucleated giant cells * ventricular arrhythmia or heart block

Answer 37

giant cell myocarditis

Question 38

most common identifiable cause of dilated cardiomyopathy in US and Europe

Answer 38

alcholic use disorder cardiomyopathy

Question 39

correlated to total lifetime dose of ethanol

Answer 39

degree of myocardial damage

Question 40

can alcohol abstinence reverse cardiomyopathy?

Answer 40

only in early stages

Question 41

trypanosomes

Answer 41

myocarditis due to chagas

Question 42

can occur in late pregnancy or up to a few months postpartum

Answer 42

peripartum cardiomyopathy

Question 43

can present one month to one year or more after termination of therapy

Answer 43

doxorubicin induced heart failure

Question 44

chemotherapy agent that can cause cardiomyopathy

Answer 44

doxorubicin

Question 45

LVH without indentifiable cause

Answer 45

HCM