Bacte Lec: Chlamydia

Question 1

Characteristic of Chlamydiae?

Answer 1

Non-motile, Gram-negative, pleomorphic, obligate intracellular parasite

Question 2

Causes avian chlamydiosis and bovine abortion and psittacosis in humans

Answer 2

Chlamydophila psittaci

Question 3

Recovered from cattle and sheep with various diseases including sporadic bovine encephalitis, infectious polyarthritis, pneumonia and diarrhea

Answer 3

Chlamydophila pecorum

Question 4

Causes enzootic abortion of sheep and goats, chlamydial abortion in cattle, pigs and goats

Answer 4

Chlamydophila abortus

Question 5

Causes intestinal infections in pigs

Answer 5

Chlamydophila suis

Question 6

Causes Inclusion conjunctivitis in guinea pigs

Answer 6

Chlamydophila caviae

Question 7

Cause of a variety of respiratory infections in humans. Similar organisms recovered from horses with respiratory infections and koalas with conjunctivitis

Answer 7

Chlamydophila pneumoniae

Question 8

Causes Conjunctivitis (feline pneumonitis)

Answer 8

Chlamydia felis

Question 9

How many serovar does Chlamydophila pneumoniae
have?

Answer 9

One serovary

Question 10

T/F: Chlamydia trachomatis
has one serovar.

Answer 10

False: Many serovars; More than 15 serovars

Question 11

Causes trachoma, inclusion conjunctivitis in infants, lymphogranuloma venereum, other genital tract infections, and proctitis in humans.

Answer 11

Chlamydia trachomatis

Question 12

Respiratory infections in mice

Answer 12

Chlamydia muridarum

Question 13

T/F: Chlamydia only have DNA.

Answer 13

Chlamydia have both RNA, DNA and cell walls like Gram negative bacteria.

Question 14

Chlamydia is capable of hydrolyzing what substances?

Answer 14

Metabolically capable of hydrolyzing glucose, pyruvate and glutamate

Question 15

Chlamydia exists in what stages?

Answer 15

Infectious & intracytoplasmic forms

Question 16

Form of Chlamydia shows elementary odies.

Answer 16

Infectious form

Question 17

Form of Chlamydia shows reticulate bodies

Answer 17

Intracytoplasmic form

Question 18

Shape and size of elementary bodies.

Answer 18

Spherical shape and 0.25 um in diameter.

Question 19

It is the dormant phase. Elementary bodies before uptake by target cell

Answer 19

Phase 1

Question 20

Elementary bodies have very little metabolic activity during this time

Answer 20

Phase 1

Question 21

What phase does this happen: Induction of metabolic activities with elementary bodies

Answer 21

Phase 2

Question 22

What phase is Characterized by transformation of elementary bodies into non-infectious

Answer 22

Phase 3

Question 23

What phase is characterized by reversion of the mature reticulate bodies back into elementary bodies which occurs within 20 to 30 hours after replication

Answer 23

Phase 4

Question 24

All chlamydiae share a ________ antigen?

Answer 24

All chlamydiae share a genus-specific antigen

Question 25

What type of antigen is used in complement fixation?

Answer 25

lipopolysaccharide (LPS) antigen used in complement fixation

Question 26

The reactive component of LPS

Answer 26

Its reactive moiety is ketodeoxyoctanoic acid (KDO).

Question 27

T/F: Toxins not demonstrated in Chlamydia, the lipid A portion of the LPS does not have endotoxic properties

Answer 27

True

Question 28

Elementary bodies produce this, while reticulate bodies do not.

Answer 28

Hemagglutininins

Question 29

Chlamydia infect what part of the body

Answer 29

mucous membranes of the respiratory system and gastrointestinal tracts of normal animals including avian species

Question 30

Where are elementary bodies shed?

Answer 30

Elementary bodies are shed in secretions and feces in small number from asymptomatic animals

Question 31

T/F: Chlamydia do not survive for long periods.

Answer 31

False: Chlamydiae can survive for long periods in the soil and feces

Question 32

Factor that degrades the host transcription factors associated with the production of major histocompatibility complex molecules (MHC)

Answer 32

Chlamydial protease activity factor (CPAF)

Question 33

What is the stained used in demonstration of organism?

Answer 33

Giemsa and Gimenez

Question 34

T/F: Enzyme-linked Immunosorbent Assay is used for antigen detection in feces

Answer 34

True

Question 34

Enzootic abortion is sheep and goats mode of infection.

Answer 34

Ingestion

Question 35

SBE means?

Answer 35

Sporadic Bovine Encephalomyelitis

Question 36

Chronic form of SBE exhibits?

Answer 36

fibrinous pericarditis, pleuritis and peritonitis

Question 37

Morbidity and mortality of SBE?

Answer 37

50%

Question 38

For smear, culture, and histopathology in SBE. What part of the body is used?

Answer 38

Brain is used, have fresh and half formalinized

Question 39

Disease of chlamydia characterized by follicular conjunctivitis with ocular discharge that may become purulent

Answer 39

Feline Pneuomintis caused by C. felis

Question 40

In feline pneuomintis ocular form is seem most commonly in what age?

Answer 40

Ocular form seen most commonly in 5-12 week old kittens

Question 41

Chlamydial infections in koalas causes?

Answer 41

Conjunctivitis

Question 42

Chlamydial infections in horses causes?

Answer 42

Respiratory infection

Question 43

In humans, __% of C. psittaci caused by exposure to _____

Answer 43

70%; exposure to caged pet birds