Behavioral Med Drugs I

Question 1

This class of drugs reduces sleep latency time

Answer 1

hypnosis

Question 2

What are some other effects of sedatives

Answer 2

prevent seizures, muscle relaxant

Question 3

Most intentional and accidental overdoses involve ____

Answer 3

polypharmacy

Question 4

This is an ultra-short action of induction of anesthesia with onset <1 minute, duration of 20 minutes

Answer 4

thiopental

Question 5

This is a short acting hypnotic lasting 3-8 hrs

Answer 5

Pentobarbital, amo/seco barbital

Question 6

This is a long acing barbituate lasting 1-2 days, was used in kids

Answer 6

phenobarbital

Question 7

What is one of the main reasons why there is a decline in the barbiturate utilization

Answer 7

high overdose potential

Question 8

What receptor type does GABA work on ?

Answer 8

GABA-A

Question 9

This is the main CNS inhibitory neurotransmitter

Answer 9

GABA

Question 10

GABA A-1 mediates this:

Answer 10

anesthesia and sedation

Question 11

GABA A-2 mediates this

Answer 11

anticonvulsants, anxiolytic actions

Question 12

These benzos have utility in sedation

Answer 12

alprazolam, and lorazepam

Question 13

This is a benzo antagonist that is used parentally needs to be available for outpatient procedures with conscious sedation and it used to reverse it.

Answer 13

flumazenil

Question 14

The first generation of antihistamines included what side effects?

Answer 14

drowsiness/sedation

Question 15

This is an H1 receptor antagonist that has strong sedation effects

Answer 15

Hydroxyzine

Question 16

This sedative has an anxiolytic effect with less cognitive dysfunction, decreased abuse potential, and less effective in panic disorders

Answer 16

Buspirone

Question 17

How long do you use hypnotic therapy

Answer 17

2 wks or less

Question 18

What non-benzo hypnotic has an increase in the incidence of depression

Answer 18

eszopiclone

Question 19

This type of depression is considered a normal reaction to tragedy

Answer 19

reactive

Question 20

This type of depression is hypothesized to be a neurotransmitter imbalance

Answer 20

endogenous

Question 21

This type of depression is alternating periods of mania and depression

Answer 21

bipolar affective disorder

Question 22

What is the main stay of bipolar tx and examples

Answer 22

mood stabilizers: lithium, anticonvulsants

Question 23

How do you tx the manic phase of bipolar disorder

Answer 23

antipsychotic drugs

Question 24

What are some cautions of lithium carbonate?

Answer 24

narrow therapeutic index, multiple drug interactions

Question 25

What are the 4 General Rules about Antidepressants?

Answer 25

1. effectiveness of each group is equal 2. none work quickly 3. side effect profiles differ significantly 4. safety issues also differ

Question 26

What adverse effect of MAOIs is similar to a thyroid storm?

Answer 26

tyramine crisis

Question 27

T/F, tyramine is in foods

Answer 27

True

Question 28

What are other indications of MAOIs?

Answer 28

neurotic disorders, PTSD, OCD, Parkinson

Question 29

What is a serious adverse effect of MAOIs?

Answer 29

overdose potential

Question 30

TCA are effective but what is a significant issue?

Answer 30

safety

Question 31

What are TCA side effects?

Answer 31

anticholinergic, orthostatic hypotension, reflex tachy

Question 32

What is the main indication of TAC?

Answer 32

chronic depression

Question 33

Name two 1st generation TCAs

Answer 33

Imipramine, amitriptyline

Question 34

What are other uses of SSRIs?

Answer 34

eating disorders, OCD, panic attacks, PMS, postmenopausal vasomotor flushes

Question 35

What are popular choices of SSRIs?

Answer 35

fluoxitine, paroxetine, sertaline, escitalopram, citalopram

Question 36

What are the SSRI side effects?

Answer 36

sleep disturbances, sexual dysfunction, almost zero risk of fatal overdose

Question 37

This antidepressant is most effective against neuropathic pain

Answer 37

SNRIs

Question 38

Examples of SNRIs

Answer 38

Venlafaxine, Duloxetine

Question 39

What are two examples of atypical antidepressants?

Answer 39

buproprion, trazadone

Question 40

This drug has potent antidepressant effects with a very rapid onset of action

Answer 40

Ketamine

Question 41

What are some other uses for antidepressants?

Answer 41

chronic pain/fibromyalgia, enuresis, smoking cessation, migraine headaches, postmenopause

Question 42

What are some suicide warnings for antidepressants?

Answer 42

highest risk in the first few months, special caution in teens/young adults

Question 43

T/F psychotropic drugs are approved for use in pregnancy

Answer 43

False

Question 44

This is seen in pt stopping or reducing the dose of antidepressants

Answer 44

discontinuation syndrome