Behavioral Med II

Question 1

This is the mos common type of psychoses

Answer 1

idiopathic

Question 2

This type of psychoses includes some endrocrine and neurodegenerative disorders

Answer 2

psychoses d/t medical conditions

Question 3

This type of psychoses is from meds, drugs, and toxins

Answer 3

toxic psychoses

Question 4

What are the two types of psychosis symptoms

Answer 4

positive and negative

Question 5

What do almost all antipsychotic drugs have as their MOA?

Answer 5

dopamine receptor D2 blocking effect

Question 6

What do dopamine agonsists aggravate?

Answer 6

schizophrenia

Question 7

This drug is approved for Parkinson’s disease psychosis and has no D2 blocking effect

Answer 7

Pimavanserin

Question 8

This antipsychotic drugs block D2 receptors and reduce dopamine in the forebrain

Answer 8

first generation antipsychotic drugs

Question 9

What are the high potency effects of first generation antipsychotic drugs

Answer 9

extrapyramidal tract- parkinson like

Question 10

What are the low potency effects of first generation antipsychotic drugs

Answer 10

sedation, hypotension, autonomic side effects

Question 11

What are the atypical agents for antipsychotic drugs called atypical?

Answer 11

less extrapyramidal effects

Question 12

What are the major problems with the atypical antipsychotics?

Answer 12

weight gain, DM, hypercholesterolemia

Question 13

1st generation antipsychotics butyronphenones

Answer 13

haloperidol

Question 14

1st generation antipsychotics thioxanthenes

Answer 14

thiothixene

Question 15

Name 3 atypical antipsychotics

Answer 15

olanzapine, risperidone, clozapine

Question 16

Antipsychotic drug side effects

Answer 16

extrapyramidal, antimuscarininc, alpha adrenenergic, dopamine inhibition

Question 17

The are antimuscarinic side effects of antipsychotic drugs

Answer 17

dry mouth, blurred vision, constipation, urinary retention

Question 18

The alpha adrenergic side effects of antipsychotic drugs

Answer 18

orthostatic Hypotension, ejaculatory dysfunction

Question 19

The dopamine inhibitory side effects of antipsychotic drugs

Answer 19

hyperprolactinemia, galactorrhea, gynecomastia

Question 20

T/F Tardive dyskinesisa may resolve after discontinuation of neuroleptic drugs lke Haldol

Answer 20

F

Question 21

What is the main cardiac effect of antipsychotics?

Answer 21

prolonged QT intervals

Question 22

What generation of antipsychotic drugs safe for pregnancy?

Answer 22

1st generation

Question 23

From the CATIE study, what drug had the lowest discontiuation rate?

Answer 23

Olanzapine

Question 24

What are the greatest risks of Olanzapine?

Answer 24

wt gain, diabetes, hyperlipidemia

Question 25

T/F, early treatment with antipsychotic drugs produces better results

Answer 25

T

Question 26

What drugs are including in the methylxanthines

Answer 26

caffeine, theophylline, theobromine

Question 27

T/F nicotine is more addictive than heroin

Answer 27

T

Question 28

What is the main benefit from the use of nicotine?

Answer 28

relief of withdrawal symptoms

Question 29

What are the side effects of Varenicline (Chantix)?

Answer 29

nausea, increased suicide ideation (?)

Question 30

What are the key chemical effects of cocaine?

Answer 30

accentuates norepinephrine, depletes dopamine

Question 31

What are the indications of amphetamines?

Answer 31

ADHD, nacrolepsy, obesity

Question 32

What is included in the withdrawal syndrome of amphetamines?

Answer 32

paranoid psychosis, resembles schizophrenia

Question 33

What drugs are associated with cognitive enhancement?

Answer 33

amphetamines, methyphenidate, modafinil

Question 34

What are the indications of the non-amphetamine drug, Modafinil?

Answer 34

narcolepsy, somnolence d/t sleep apnea, work shift related somnolence

Question 35

What are the 3 stimulant commonalities?

Answer 35

addiction, withdrawal, used/abused