Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

BGM1002-Biochemistry > BGM1002/L05 Enzymes I > Flashcards

BGM1002/L05 Enzymes I Flashcards

1
Q

Give 2 examples of structural proteins.

A

Keratin
Collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Give 2 examples of contractile proteins.

A

Actin
Myosin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What can the activity of enzymes be controlled by?

A

Host organism
External intervention/environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How do many drugs and poisons work?

A

Enzyme inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How does haemogglutanin work?

A

Interacts with cell membrane
Inserted into cell membrane
Interacts with other proteins in cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What protein facilitates the entry of influenza into cells?

A

Haemagglutanin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What protein facilitates the exit of influenza from host cells?

A

Neuraminidase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which 2 anti-flu drugs target the neuraminidase enzyme of influenza? By which mechanism?

A

Tamiflu & Relenza
Competitive inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which section of penecillin-binding proteins interact with the active site?

A

Beta-lactam ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How do penecillin-binding proteins work?

A

Catalyse cross-linking of peptide component to glycine cell wall in bacteria
Cells weaken and lyse due to lack of crosslinks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which enzyme breaks down Penecillin in penecillin-resistant bacteria?

A

Beta lactamase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What kind of bacteria can develop penecillin resistance via beta lactamase?

A

Gram negative bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How does Penecillin work?

A

Inhibits enzyme necessary for cell wall formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

By which mechanism do nucleoside analogue drugs work?

A

Irreversibly bind to active site

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Give 3 examples of anti-viral drugs.

A

AZT/ Azidothymidine
Acyclovir
Remdesvir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is Keq?

A

Equilibrium constant
Ratio of products over reactants
Correlated with energy released by a reaction.

17
Q

What is the equation for Gibb’s Free Energy Change?

A

Change in G= -RT(LnKeq)

18
Q

What determines reaction rate?

A

Activation energy (AE)

19
Q

How do catalysts work?

A

Lowering activation energy by providing an alternative reaction pathway

20
Q

How do enzymes lower AE?

A

Bind reactant
Stabilise reaction intermediate

21
Q

How is Keq affected by enzymes?

A

No effect

BGM1002-Biochemistry (29 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions