Biliary Cancers Flashcards Preview

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Flashcards in Biliary Cancers Deck (4):
1

How is diagnosis of biliary cancers made?

Radiological investigations & pathomorphological assessment

Final pathological Dx needed before Chemo/RT/non-surgical oncological therapy.
** Not critical for planning surgery in patients with characteristic findings of resectable biliary cancers **

2

Risk factors for cholangiocarcinomas

Primary sclerosing cholangitis (30% of all cholangiocarcinomas)
Congenital anomalies of biliary tree (eg. Choked octal cysts)
Liver fluke disease --> chronic inflammation of bile duct
Hepatolithiasis
Toxins
Lych Syndrome, Biliary papilloma toss
Chronic liver cirrhosis
DM
Obesity metabolic syndrome
HIV

3

Name the liver fluke that causes cholangioCA

Opisthorchis Viverrini

4

Contraindications to Surgery in cholangiocarcinomas?

Vascular involvement
Distant spread
Extent of local spread