Rectal Cancer Flashcards Preview

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Flashcards in Rectal Cancer Deck (4):
1

What did the German Rectal Cancer Study group show?

Neoadjuvant prolonged course RT with 5FU-based chemotherapy for T3+/N0-2 rectal cancer

Local Recurrence rates and toxicities are more favorable with neoadjuvant ChemoRT
OS similar for neoadjuvant CRT cf postop CRT

2

When should transanal excision should be considered?

Select patients with:
- Early stage Rectal CA
- small real CA

3

Is adjuvant therapy needed after transanal resection?

NO.

After transanal resection of appropriately selected patients with early-stage rectal cancer, no further therapy required

4

What is the standard therapy for early localized squamous Ca of the anus?

ChemoRT with 5FU & Mitomycin
- a/w excellent cure rates

Salvage APR reserved for recurrent anal cancer