Biliary disease Flashcards Preview

Gastrointestinal > Biliary disease > Flashcards

Flashcards in Biliary disease Deck (14):
1

What is PBC?

Damage to bile ducts, causing scarring and obstruction of bile outlfow

2

How does PBC present?

Most common in middle age women
Normally an incidental finding
Symptoms; Itch, fatigue, xanthelasma

3

How do you diagnose PBC?

Positive autoantimitochondrial antibodies
Abnormal LFTs
Liver biopsy

4

How do you treat PBC?

Urseodeoxycholic acid

5

What is primary sclerosing cholangitis?

Autoimmune destruction of large and medium sized bile ducts

6

What is the clinical presentation of PSC?

Recurrent cholangitis

7

How do you diagnose PSC?

Imaging of the biliary tree

8

How do you treat PSC?

Maintain bile flow
Monitor for cholangiocarcinoma and colo-rectal cancer

9

Why do we get gallstones?

Abnormal bile composition
Bile stasis
Infection
Excess cholesterol
Excess bilirubin

10

What are the common risk factors for gallstones?

Age
Female
High fat diet
Obesity
Pregnancy
Hyperlipidaemia
Crohn's disease
Diabetes

11

What are the 5 Fs of gallbladder disease?

Fair, fat, female, fertile and over forty

12

How do you diagnose gallstones?

Ultrasound
CT scan
MRCP/ERCP

13

What are the four stages of cholangiocarcinoma?

I - Below the confluence
II - Confined to confluence
III - Extension into right or left hepatic ducts
IV - Extension into both the right and left hepatic duct

14

What is the only curative treatment for cholangiocarcinoma?

Surgical bile duct and liver ressection