Liver Tumours Flashcards Preview

Gastrointestinal > Liver Tumours > Flashcards

Flashcards in Liver Tumours Deck (22):
1

Name 4 benign liver tumours

Hemangioma
Focal nodular hyperplasia
Adenoma
Liver cysts

2

What kind of hepatobiliary cancers are there?

Hepatocellular carcinoma
Cholangiocarcinoma
Metastases

3

What are hepatic adenomas?

Normally fat containing lesions of the liver

4

Which lobe are adenomas more likely to occur on?

Right

5

What common group of drugs are hepatic adenomas associated with?

Oral contraceptives and androgenic steroids

6

How do you diagnose hepatic adenomas?

Ultrasounds, CT , MRI and maybe FNA (Fine needle aspiration biology)

7

How do you treat hepatic adenomas?

Stop hormone treatment
Observe every 6 months for 2 years
If there is no regression then surgery is required

8

What are the three kinds of polycystic liver disease?

Von Myenburg complexes
Polycystic Liver Disease
Autosomal dominant polycystic kidney disease

9

What causes polycystic liver disease?

Embryonic malformation of the intrahepatic biliary tree.

10

What is polycystic liver disease?

The occurence of numerous cysts throughout the liver parenchyma

11

Describe Von Meyenburg complexes (VMC)

Multiple benign cysts throughout the liver.
Usually an incidental finding

12

What is the difference between polycystic liver disease and autosomal polycystic kidney disease?

PCLD preserves liver function whilst renal failure is rare.

ADPKD causes renal failure and hepatomegaly

13

How do patients with PcLD present?

Abdominal pain and distension

14

How do you treat PcLD?

Prevent cyst growth and alleviate symptoms
Transplant or aspiration is sometimes necessary in cases with advanced PCLD, ADPKD or liver failure.

15

How do patients with a liver abscess present?

Pyrexia
Leukocytosis (High WBC)
Abdominal pain
History may show abdominal or biliary infection or previous dental procedure.

16

How do you treat liver abscesses?

Broad spectrum antibiotics and drainage
If there is no improvement surgical drainage and 4 week antibiotic therapy is required

17

What is the biggest risk factor for hepatocellular carcinoma?

Cirrhosis from any cause

18

Where can HCC metastaise to?

Rest of the liver
Portal vein
Lymph nodes
Lung
Bone
Brain

19

What is the tumour marker for HCC?

Alfa feto protein AFP

20

How do you diagnose HCC?

AFP
US
CT
MRI
Biopsy

21

What are the 5 stages of HCC and how do you treat them?

Stage 0 = Ressection or transplant
Stage A-C =Transplant, ablation, chemotherapy
Stage D = Management of symptoms

22

What is the best available treatment for HCC?

Liver transplant