Flashcards in Hepatitis Deck (24):
What is the first test performed in the diagnosis of Hepatitis?
Hep Bs Ag
(postive surface antigen shows active disease acute/chronic)
What does a high viral load mean?
Patient is highly infective
What does a positive Hep Bs Ab mean?
The patient has either recovered from an acute infection or has been immunised
How can you tell the difference between someone who has been immunised and a recovered hepatitis patient?
Those who have recovered will had the Hep B core Ab whereas those who have been immunised will not
How is Hep A spread?
A for Arse
What are the risk factors for Hep A?
IV drug users
Is Hep A acute or chronic?
How do you diagnose Hep A?
Clotted blood for serology
(Gold top vacutainer)
Look for Hep A IgM
How do you control Hep A?
Improve hygiene and provide prophylactic vaccination
Where is Hep E most common?
How does Hep E present clinically?
Like hep A
How is Hep E spread?
When do you find Hep D?
In patients with Hep B
How is Hep B spread?
Mother to child
What are the risk factors for Hep B?
Multiple sexual partners
IV drug users
Children of infected mothers
How can you control Hep B?
Prevent needle exchange
Screen pregnant women
Is C acute or chronic?
How is hep C spread?
The same as Hep B
What is the management for Acute Viral Hepatitis?
Monitor for encephalopathy and further infections
Notify public health
What is the management of chronic viral hepatitis?
Vaccinations for other hepatitides
Reduce alcohol intake
Screen for cancer
When is antiviral treatment used in the treatment of hepatitis?
At risk of complications
Without contraindications (cancer)
Have correct attitude
You must treat before complications and when there is evidence of inflammation
What are the main antivirals used in hepatitis and what are their side effects?
Peginterferon - Flu like symptoms
Ribavirin - anaemia
Telaprevir and Boceprevir - Rash and anaemia
What is peginterferon?
A long acting interferon that is normally produced by the body in response to viral infections