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Flashcards in Biochem - nutrition Deck (15):
1

Vitamins stored in the liver

Folate and B12

2

Night blindness, dry/scaly skin, corneal degradation

Vit. A deficiency

3

Used to treat measles and AML subtype M3

Vitamin A

4

impaired glucose breakdown affects highly aerobic tissues first (brain, heart)

Thiamine (B1) deficiency

used in alpha-keotglutarate dehydrogenase, transketolase, pyruvate dehydrogenase

5

Cheliosis (inflammation of lips, scaling of ends of mouth), corneal vascularization

Riboflavin (B2) deficiency

6

Used as cofactor in redox reactions

Riboflavin is a component of FAD and FMN

7

Glossitis, pellagra (dermatitis, dementia, diarrhea)

Niacin (B3) deficiency

constituent of NAD/NADP

lowers levels of VLDL and raises HDL (take aspirin to prevent flushing)

8

Component of coenzymeA (CoA) and fatty acid synthase

Pantothenic acid (B5)

9

Consulsions, peripheral neuropathy, sideroblastic anemia (decr. Hgb synth/iron excess)

Pyridoxine (B6) deficiency

used in synthesis of neurotransmitters, heme, niacin, histamine, cystathione

10

Vitamin deficiency caused by excessive ingestion of eggs or antibiotic use

Biotin (B7)

Caused by avidin

used as a cofactor in carboxylation reactions

11

Megaloblastic anemia w/o neuro symptoms, incr. homocysteine w/ normal MMA levels

Folate (B9) deficiency

seen in alcoholism/pregnancy

12

Megaloblastic anemia w/ neuro symptoms (parasthesias, subacute combined degeneration), incr. homocysteine and incr. MMA levels

Cobalamin (B12) deficiency

seen in alcoholism

13

Corkscrew hair, swellen gums, bruising, petechiae

Vit. C deficiency

decr. hydroxylation of proline and lysine in collagen synthesis (rough ER)

14

Hemolytic anemia, acantholysis, muscle weakness, posterior column/ST tract demyelination

Vitamin E deficiency

15

Delayed wound healing, hypogonadism, decr. adult hair

Zinc deficiency