BioCog 2A neurotransmission Flashcards
(44 cards)
1
Q
soma
A
- cell body
2
Q
axodentric
A
- axon + dendrite
3
Q
axosomatic
A
- axon + soma
4
Q
microtubule
A
- transport vesicles to presynaptic membrane
5
Q
vesicles
A
- contain neurotransmitter
6
Q
exocytosis
A
- outflow of neurotransmitters
7
Q
kiss and run
A
- immediately go back
8
Q
merge and recycle
A
- stay for little longer
9
Q
bulkendocytosis
A
- take part of the membrane with them
10
Q
Na+
A
= sodium
- postsynaptic membrane
- EPSP
11
Q
Ca2+
A
= calcium
- presynaptic membrane
- EPSP
12
Q
Cl-
A
= chlorine
- IPSP
13
Q
metabotropic receptors
A
- open ion channels indirectly
- by G protein or 2nd messenger
14
Q
G protein
A
- released by NT
- alpha unit breaks off
- opens ion channel
15
Q
2nd messenger
A
- alpha unit of a G protein activates it
- then opens ion channel
16
Q
AChE
A
- splits ACh
- only example for enzym degredation
17
Q
autoreceptors
A
- metabotropic
- either activate reuptake transporters
- or reduce NT release
18
Q
Ach
A
- learning, motor
19
Q
monoamines
A
- catecholomines
-> dopamine, norepinephrine, epinephrine
idolamines
-> serotonine
20
Q
dopamine
A
- reward, motor
21
Q
norepinephrine
A
- alertness
- fight/flight
- SNS
22
Q
epinephrine
A
- flight/fight
- SNS
23
Q
serotonine
A
- mood
24
Q
aminoacids
A
- glutamate
- gylcine
- GABA
25
glutamate
- excitatory
| - mptor
26
gylcine
- inhibitory
- motor
- only in spine
27
GABA
- inhibitory
| - motor
28
neuromodulators
- wander through brain
- dont cause potentials
- hormones or nucleosides
29
vasopressine
- hormone
| - aggression
30
oxytocine
- hormone
| - bonding
31
ligand
- chemical that binds to receptors
32
competitive binding
- binds to neurotransmitter site
33
non-competitice binding
- binds to other side
34
- L-DOPA
- dopamine prescursor
| - > indirect agonist
35
black widow venom
- stimulates ACh release
| - > indirect agonist
36
nicotine
- simulates postsynaptic ACh receptors
| - > direct agonist
37
indotoxon
- blocks norepinephrine autoreceptors
| - > indirect agonist
38
cocaine
- block dopamine reuptake
| - > indirect agonist
39
physotigmine
- inactivates AChE
| - > indirect agonist
40
reserpine
- prevents monoamine storage in vesicles
| - > indirect antagonist
41
botulinum toxin
- inhibits ACh release
| - > indirect antagonist
42
curare
- blocks postsynaptic receptors
| - > direct antagonist
43
PCPA
- inhibits serotonine synthesis
| - > indirect antagonist
44
apomorphine
- stimulates dopamine autoreceptors
| - > indirect antagonist
