Flashcards in biostatistique Deck (145)

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1

## standard deviation normal distribution a 68%

### SD a 1 from the mean

2

## standard deviation normal distribution a 95%

### SD a 2 from mean

3

## standard deviation normal distribution a 99,7%

### SD a 3 from the mean

4

## example mean a 230 mg/dl pour le cholesterol and SD a 10,what's the value for cholesterol if observations are 95%

### 210-250

5

## disease with increasing prevalence and stable incidence what happened(2)

###
any rx which prolongs life

good quality of care

6

## Quid of PPV(2)

###
positive predictive value

pobability of having the disease if the result test is positive

7

## quid of negative predictive value

### probability of having the disease if the test is negative

8

## quid of null hypothesis

### no relationship between exposure and outcome

9

## example of null hypothesis

### CRP high and colon cancer ,no relationship

10

## what to consider when evaluating the effectiveness of new trial drug

### the natural history of the disease

11

## example drug effectiveness and drug trial(2)

###
effectiveness of antiviral drug and flu

no exact conclusion can be drawn becausecommon cold is a self limited disease

12

## in hazard ration interpretation what are the 2 key factors to consider(2)

###
control arm

rx arm

13

## quid of hazard ratio <1

### the event will occur in the control arm

14

## quid of hazard ratio > 1

### the event will occur in the rx arm

15

## practice of hazard ratio

### the chance for an event to occur during taking a drug for instance

16

## interpretation of hazard ration close to one

### no difference for an event to occur in the 2 groups rx arm and control arm

17

## what information is critical to successfull randomization

### baseline characteristics

18

## what an ideal randomisation

### process to minimize selection biais and achieves possibility of cofounding variables

19

## a study is done using placebo and Rx,the assignment of the rx in teh two arm is done randomly using numbers generated by computer what randomization helps to do in ths case?

### to eliminate confounder

20

## what methods are used to eliminate cofounder during analytic stage of study

###
stratified analysis

modeling

21

## what methods are used to eliminate cofounder during adesign stage of study(3)

###
matching

restriction

randomization

22

## clue for randomization(2)

###
Rx group

Placebo group

23

## when using randomization

### during clinical trials

24

## quid of restriction

### when you limit your study to one group for example one sexe is considered

25

## problem with restriction

### you cannot generalize your finding in the population

26

## when using matching

### control studies

27

## importance in using macthing(2)

###
when you want to study risk factor(

exposure and outcome

28

## practice of macthing

### you will take a group with a known risk factor and another one without it and compare

29

## quid of false negative

### the test is negative but you have the disease

30