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usmle step 2 > Dermatologie > Flashcards

Dermatologie Flashcards

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1
Q

quid of herpes zoster

A

rash along dermatomal distribution

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2
Q

other name of herpes zoster

A

shingles

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3
Q

rx of shingles(3)

A 
acyclovir
or
valacyclovir
or
famcyclovir
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4
Q

patient with sore throat ,after receiving amox develops rash dx?

A

hypersensitivity type 1

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5
Q

rx of hypersentivity syndrome in a patient taking amox

A

antihistaminic

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6
Q

when anti histaminic is good in allergy

A

when you have no systemic symptom

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7
Q

drugs most commonly implicated in hypersensitivity type 1 reaction(5)

A 
B lactam
neuro mxar blocking agents
quinolones
chemo drugs containing platinum
foreign protein chimeric antibodies
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8
Q

disease associated with acnthosis nigricans(2)

A

condition associated with insulin resistance

GI malignancy

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9
Q

condition associated with insulin resistance(2)

A

Diabete type 2

OMPK

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10
Q

disease or state associated with multiple skin tags(3)

A

insulin resistance
pregnancy
chron disease(peri anal fissure)

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11
Q

skin condition associated with Hep C

A

porphyrie cutanea tarda

cutaneous leucocytoclastic vasculitis secondary to mixed cryoglobulinemia

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12
Q

condition associated with cutaneous leucocytoclastic vasculitis

A

palpable purpura

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13
Q

disease associated with dermatitis herpetiforme

A

celiac disease

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14
Q

skin manif associated with HIV(2)

A

severe seborrheic dermatitis

sudden onset of severe psoriasis

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15
Q

disease associated with explosive itchy seborrheic keratosis

A

GI malignancy

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16
Q

disease associated with pyoderma gangrenosum

A

IBD

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17
Q

quid of skin tag

A

pedonculated outgrowth of normal skin

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18
Q

flushing of the skin caused by hot drinks,heat and emotion

A

rosacea

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19
Q

rx of rosacea

A

topical metronidazole

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20
Q

quid of rosacea

A

telangiectasia over cheeks chin and nose

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21
Q

actinic keratosis(3)

A

sunexposed areas
sandpaper like texture
squamous cell carcinoma

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22
Q

second most common cause of ca in the US

A

SCC

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23
Q

risk factor for SCC

A

sunlight exposure

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24
Q

biopsy of SCC of skin

A

polygonal cell withb atypical nuclei at all levels of the epidermis with zone of keratinization

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25
the more agressive ca of the skin
SCC
26
rx of cellulitis with systemic symptom(2)
IV nafcilin or cefazolin
27
cellulitis with systemic Symptom and MRSA rx?
IV vancomycin
28
physio patho of bullous pemphigoid
IGG and C3 deposits at the dermal epidermal junction
29
medication which can trigger bullous pemphigoid(4)
furosemide NSAIDS captopril penicillamine
30
localisation of bullae in BP
subepidermal
31
workup for bullous pemphigoid
direct immunofluorescence
32
necrotizing fascitis
pain and fever in the zone of a trauma
33
clue for NF
purplish discoloration of the skin with gangrenous changes
34
best rx of NF(2)
debridement | antibio
35
bugs causing necrotizing facitis(3)
staph aureus group A strepcocci anaerobes
36
what test to perform in necrotizing fasciitis
check for diabetes
37
antibio used in Necrotizing fasciitis(2)
ampi sulbactam plus clyndamycin
38
cause of idiopathic necotizing fasciitis(2)
srotal or Penile NF
39
Rx of scabies
5% permethrin cream
40
patient of chronic lip ulceration(3)
malignant chronic infection autoimmune
41
cause of malignant lip ulceration
SCC
42
biopsy for SCC
invasion cords of squamous celle with keratin pearls
43
sun exposure occupation plus isolated vermillon ulcer(zone of lower lip)
SCC
44
biopsy for BCC
spindle cells surrounded by palissade basal cells
45
type of acne(3)
comedones inflammatory acne nodular cystic acne
46
rx of comedal acne
topical retinoids
47
quid of inflammatory acne
inflamed papules and pustules
48
RX of inflammatory acne (mild)(2)
topical retinoid plus benzoyl peroxid
49
moderate inflammatory acne rx(3)
topical retinoid plus benzoyl peroxid plus topical antibio
50
topical antibio used in moderate inflammatory acne(2)
clyndamycin | erythromycin
51
severe inflammatory acne rx(3)
``` topical retinoid plus benzoyl peroxid topical antibio plus oral antibiotherapy ```
52
quid of nodular cystic acne
large nodule > 5mm ,can appear cystic
53
rx of moderate nodular cystic acne(3)
topical retinoids topical antibio benzoyl peroxyde
54
rx of severe nodular cystic acne(4)
topical retinoids topical antibio benzoyl peroxyde plus oral antibiotherapy
55
rx of nodular cystic acne rebelle au rx for severe cystic acne next step
add oral isotretinoin
56
quid of herpetic withlow
viral infection of the hand
57
profession at risk for herpetic withlow(2)
dentist | health worker with direct contact with orotracheal lesion
58
Dx of herpetic withlow
cytodiagnostic de TZANCK
59
cause of herpetic withlow
herpes virus type 1 et 2
60
skin lesion in PBC(2)
xanthoma | xanthelasma
61
quid of xanthelasma
benign lesion of medial eyelid characterised by lipid filled macrophages in the dermis
62
why can you have osteoporosis in PBC
inability to absorb fat soluble vit specially vit D
63
cause of angioedema
C1 inhibitor deficiency
64
Symptom of angioedema(3)
face swelling laryngeal edema edema of bowel
65
cause number 1 of acquired angioedema
ACE inhibitor
66
physiopatho of edema in hereditary angioedema(3)
no C1 inhibitor lots of C2b and bradikiine are produced---> edema
67
causes triggering hereditary angioedema(3)
dental procedure infection trauma
68
disease causing C1Q depressed
lupus
69
patient taking drugs for acne develops redness and swelling of the skin when exposure to sun dx?
drug induced phototocixity
70
drug causing phototocic drug eruptions
all cyclines
71
cherry hemangioma appearrance
ti point rouje anba po w
72
strawberry hemangioma
bigger than cherry hemangioma
73
patient presenting difficulty respiratoire and facial edema 2 weeks after beginning ACE inhibitor
ACE inhibitor angioedema
74
why in the same vignette patient has rash problem you dont pick aspirin as the right answer
rash in aspirin appears immediately after taking the drug
75
how ace inhibitor causes angioedema
by inhibiting ACE you have high level of bradikinin
76
when angioedema with ace inhibitor can occur
at any time
77
clue for tinea versicolor
hypopigmented macules that don't tan and don't appear scaly but scale on scraping
78
bug causing tinea versicolor
malasezia furfur
79
Dx of tinea versicolor(2)
KOH preparation | spaghetti or meat balls appearrance
80
rx of Tinea versicolor
selenium sulfide lotion
81
patient with redness and blisters on breast and thighs ,patient taking warfarin
warfarin induced necrosis
82
condition associated with warfarin induced necrosis
protein C deficiency
83
lieu of warfarin induced necrosis(4)
breast thigh buttocks abdomen
84
rx of frostbite
rapid rewarm with warm water (40-44 C)
85
rx of dermatite herpetiforme(2)
dapsone | gluten free diet
86
causativ agent of molluscum contagiosum
poxvirus
87
risk factor for molluscum contagiosum
AIDS with CD4 less than 100
88
rx of molluscum C(2)
curretage or application of liquid nitrogen
89
lesion in Molluscum C
papules with central umbilification
90
patient with mole becoming larger what skin examination clue would be more consistent with malignancy
zones of different skin colors
91
features of melanoma(5)
``` Asymetric lesions Border irregularities Color variegation Diameter > 6 mm Enlargement or evolution of skin lesion ```
92
quid of tinea corporis
circular lesion with scaly borders and central clearing
93
bug in tinea corporis
trichophyton rubrum
94
rx of tinea corporis(2)
topical terbinafine 2% plus oral griseofulvine
95
clue for seborrheic keratosis(4)
warty appearance waxy well circumscribed stuck on appearance
96
localisaion of herpes simplex(2)
mouth | genital area
97
bug causing chicken pox
varicella zoster (varicelle)
98
quid of shingles
reactivation of varicella zoster
99
pruritic circumferantial rash over wrist
allergic contact dermatidis
100
most commonly involved substance in contact dermatidis(2)
poison ivy | nickel jewelry
101
type of hypersensitivity in allergic contact dermatidis
type 4
102
cells inplicated type 4 hypersensitivity
lymphocyte T
103
rx allergic contact dermatidis(3)
calamine antihistamines topical steroids
104
use of oral steroid in contact dermatidis
in sever case
105
quid of stevens jhonson syndrome
erythema multiform major
106
clue for stevens jhonson syndrome(2)
Mucocutaneous lesion plus target shaped lesions
107
quid mucocutaneous lesion in steven jhonson syndrome(3)
conjonctivitis pa ka pipi paka vale
108
quid of erythema multiform minor(4)
rash occuring after herpes infection target lesions are present mucosal invlovement no systemic symptom
109
patient after working in woods develops vesicules on forearms vesicule full with coagulase negative organism dx
contact dermatidis
110
substance found in wood causing contact dermatidis(2)
sumac | woody shrug
111
why you foun coagulase negative bacteria in vesicle fluid in contact dermatidis
secondary infection by S epidermidis
112
definition of ichtyosis(2)
dry skin and scaly worst during winter season | dry skin with horny plates on the extensor surfaces of limbs
113
clue for senile purpura
ecchymosis in older patient with nothing else
114
cause of senile purpura(2)
perivascular connective tissue atrophy | loss of elastic fiber
115
other name of senile purpura
solar or actinic purpura
116
rx of senile purpura
no rx needed
117
clinic of senile purpura(2)
brown discoloration | dark purple of skin
118
disease associated with vitiligo(6)
``` pernicious anemia thyroid disease diabete type 1 primary adrenal insufficiency hypopituitarism alopecie areata ```
119
thyroid disease associated with vitiligo(2)
graves | autoimmune thyroiditis
120
quid of chalazion
obstruction of mebomian gland
121
CAT in case of reccurent chalazion
meibomian gland carcinoma | also called sebaceous carcinoma
122
best test in case of reccurent chalazion
histopatho
123
Dx differential of chalazion
BCC of the eyelid
124
the most common tumor of the eyelid
BCC
125
most common tumor in mankind
BCC
126
pathology of vitiligo
autoimmune destruction of melanocytes
127
if you see changing mole what to think
eliminer melanoma
128
most commonly drug involved in SJ syndrome(3)
sulfonamide NSAIDS Phenytoin
129
drug causing toxic epidermal necrolysis(2) TEN
same as SJ syndrome | barbiturate
130
Between TEN and SJS difference
up to 10 % of the body involved=SJS | more than 30%=TEN
131
nickolsky sign
patches of skin slide off with slightest pressure
132
after marrow transplantation patient develops diarrhea and pruritic maculopapular rash Dx
graft versus host disease
133
physiopatho of graft versus host disease
recognition of host major and minor HLA antigens by donor T cells and activation of T cells and cell mediated immune response
134
target of graft versus host disease(3)
foie intestin peau
135
waxy loose scaleswith erythema of scalp ,central face umbilicus interscapular area body fold presternal region dandruft in hair
dermatidis seborrheic
136
disease associated with seborrheic dermatidis(2)
HIV | Parkinsonism
137
immunologic condition associated with M contagiosum
cellular immuno deficiency chemo corticosteroid use
138
patient with slightly elevated lesion ,brown colored measuring > 7mm,with irregular border Dx
Melanoma
139
study of Melanoma
excisionnal biopsy with narrow margin
140
study for melanoma with less than 1 mm depth
excision on 1 cm tumor free margin
141
study for melanoma with more than 1 mm depth
look for a lymph node sentinel study
142
vulgaris pemphigus(2)
flaccid bullae | slightly rubbing of the involved skin causes easy separation of the epidermis=nickolsky sign
143
immunofluorecence finding in pemphigus vulgaris
IGG deposits intercellular in the epidermidis
144
target of antibody in Pemphigus vulgaris
desmoglein
145
Rx of Pemphigus vulgaris
steroids | or azathioprine plus prednisone plus metotrexate
146
flaccid blister
P vulgaris
147
tense blister
P Bullous
148
bug causing acne
propionibacterium acne
149
clue for porphyria cutanea tarda(2)
painless blister of hand | hyperpigmentation hypertrichosis
150
rcause of PCT
deficiency in uroporphyrinogen decarboxylase
151
role of uroporphyrinogen decarboxylase
heme synthesis
152
trigger of PCT
alcohol | estrogen
153
rx of PCT(3)
hydroxychloroquine or phlebotomy interferon @ to rx Hep C
154
Clue fro Necrotizing fasciitis
patient after trauma in leg develops pain and fever
155
rx of scabies
5% permertrin cream
156
general measure for scabies
bedding and clothing should be cleaned or set aside for 2 weeks
157
quif edema producing factor in angioedema(2)
c2B | bradikynin
158
rx of tinea versicolor
selnuim sulfide | ketoconazole shampoo
159
physiopatho of SJS
immune complex mediated
160
quid of stye or Hordeolum(orgelet)
acute infection of eyelids glands
161
zone bastion du psoriasis(5)
``` scalp oreille coude genou organes genitaux ```

usmle step 2 (22 decks)

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