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Flashcards in Blood and Lymph 2 Deck (18):

monocytes: what? arrive when? do what?

highly mobile phagocytic cells. arrive at site shortly after neutrophils. release chemicals to attract other phagocytes, and fibroblasts (to make collagenous scar tissue)


lymphocytes: what type of immunity? 3 cell types

specific aka adaptive: will target specific antigens. T cells, B cells and NK cells.


platelets come from? found where?

megakaryocytes in bone marrow. 1/3 in spleen and other vascular organs, otherwise in blood


platelets: are what?

membrane bound enzyme packets that pinch off from cytoplasm of the megakaryocyte


body fluids: two categories?

intracellular (cytoplasm, nucleoplasm). extracellular: blood plasma and interstitial fluid


lymphatic system: 3 roles

produce/maintain/distribute lymphocytes. assist with maintaining normal blood volume. alternate route of transport of hormones, nutrients and metabolic waste


how does lymphatic system help maintain normal blood volume

vascular pressure forces water/solutes across capillary membrane into interstitial fluid, and lymph vessels return that fluid to the vasculature


lymph flow vs. blood flow

blood: actively pumped through vessels by heart. lymph: flows passively along pressure gradient, no pump.


lymphatic vessels: thickness? pressure? backflow?

vessels are very thin: system under super low pressure. lots of valves to prevent backflow


interstitial fluid: called ___when it enters ___? majority of cells are?

called lymph when it enters the lymphatic vessels. 99% cells are lymphocytes. 1% macrophages, eosinophils and neutrophils


lymphocytes: primary aka ___ structures do what? secondary aka __structures do what?

central: produce, maintain and store lymphocytes. peripheral:where most immune responses are initiated


primary central structures for lymphocytes: contain? lymphoid organs include?

contain stem cells to generate B, T and NK cells. bone marrow, thymus gland, spleen


largest lymphoid organ is the? function?

spleen: filters blood (removes abnormal blood cells by phagocytosis). stores iron recycled from metabolized RBCs. initiates immune response by B/T cells


lymph nodes: what? structure?

oval lymphoid organs from 1 - 25 mm in diameter. lots of afferent vessels penetrating a fibrous capsule, and a single efferent vessel exiting


lymph nodes: what do they do? where cells are located?

filter the lymph, remove 99% or more of antigens. T cells in cortex while B cells and macrophages are in the medulla


lymphoid tissue: what? two types?

connective tissues dominated by lymphocytes. can be diffuse, or nodules


diffuse lymphoid tissue: where

mucous membranes of respiratory and urinary tracts


lymphoid tissue nodules: what? where?

oval shaped aggregations of densley packed lymphocytes. mucosa of digestive tract like in tonsils, lining of small intestine aka peyer's patches and appendix