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Flashcards in CBC 1 Deck (19):
1

CBC: stands for? generated when?

complete blood count, blood run through a coulter counter and generates a count of the number of cells in blood

2

normal CBC derived from?

averaging cell counts measure in a normal healthy population +/- two standard deviations = around 5% of normal population will still lie outside standard reference range

3

normal reference ranges: variation?

will vary by gender, age, ethnicity, gestational status. are also lab/instrument specific

4

cytopenia: def? 4 subcategories?

low blood cell count. anemia = low hemoglobin. thrombocytopenia = low platelets. leukopenia = low white cells. neutropenia = low neutrophils.

5

increased cell counts: 4 examples?

neutrophilia. erythrocytosis = increased RBC. polycythemia = increased hematocrit. thrombocytosis = increased platelets.

6

CBCd?

complete blood count with differential (white cells are counted and categorized and quantified into their subtypes)

7

most common way of quantifying RBCs?

hemoglobin aka Hb aka HGB. amount of Hb protein in g/L

8

HCT

hematocrit: proportion of total that is occupied by RBCs. usually around 0.4 - 0.5

9

MCV

mean cell volume = average RBC size in femtoliters = the most clinically important, helps us classify anemia

10

MCHC

mean cell hemoglobin concentration; not commonly referred to

11

RDW

red cell distribution width; variation in size of red cells

12

anemia: definition? numbers for men/women?

low hemoglobin: men below 130g/L, women

13

normal MCV

80 - 100 fL

14

platelets: life span? purpose?

7-10 days. after blood vessel injury, they form a plug and coagulation factors are activated on their surface to form a fibrin net = blood clot

15

5 types of WBCs seen under microscope

neutrophils. lymphocytes. monocytes. eosinophils. basophils.

16

abnormal WBCs

blasts, myeloids. abnormal, reactive or variant lymphocytes which can be benign or malignant.

17

neonate: difference in CBC?

very high Hb levels, high MCV at birth --> falls of quickly after first few days of life

18

1 year old: difference vs. adult CBC?

relatively lower Hbs and lower MCVs

19

children less than 5 years of age vs. adult CBCs?

higher overall WBC, more lymphocytes than neutrophils (reverse of adults)