Blood Cell Components: Interpreting a CBC Exam 3 Flashcards

(33 cards)

1
Q

what is the type of red blood cell

A

erythrocytes

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2
Q

how are erythrocytes shaped

A

like a doughnut with middle jelly like part

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3
Q

how are erythrocytes measured

A

in percentages called a hematocrit

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4
Q

what is the primary responsibility of red blood cells

A

TISSUE OXYGENATION

carries hemoglobin which carries oxygen to every tissue in our body and “feeds” the tissues cause tissues need oxygen

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5
Q

what are white blood cells also called

A

leukocytes

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6
Q

what is the primary role of white blood cells

A

to protect –> immune function

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7
Q

what are the 5 white blood cells

A
Neutrophils
Lymphocytes
Monocytes
Eosinophils 
Basophils
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8
Q

what is the pneumonic to remember white blood cells

A
Never : Neutrophils
Let : Lymphocytes
Moneys : Monocytes
Eat : Eosinophils
Bananas : Basophils
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9
Q

what are granulocytes

A

white blood cells that have cells with nucleus and several lobes and granules

they release mediators with inflammatory and immunity properties

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10
Q

which white blood cells are granulocytes

A

neutrophils (50-67%)
eosinophils (0-3%)
basophils (0-2%)

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11
Q

what are agranulocytes

A

white blood cells with nucleus but little to none granules

do not release mediators

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12
Q

which white blood cells are agranulocytes

A

lymphocytes (24-40%)

monocytes/macrophages (4-9%)

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13
Q

Describe neutrophils

A

most prevalent; first to arrive at site of inflammation
bands (immature) and segs (mature)
increase with acute bacterial infections and trauma
-EX. if I get strep (bacterial); neutrophil count will go up
shift to the left (increase of bands)
-very acute/early stage of infection; more immature than mature

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14
Q

describe lymphocytes

A

T and B cells
primary cells of immune response

increase with chronic bacterial infection and acute viral infection
Agranulocytes
EX. MRSA = more lymphocytes

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15
Q

describe monocytes

A

potent phagocytosis cells
-phagocytosis - eat all the junk that other cells are clearing up

increase with bacterial infections & cancers

Agranulocytes

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16
Q

describe eosinophils

A

increase with allergic reactions or parasitic infections

THINK: Worms, Wheezes, and Weird Diseases

17
Q

describe basophils

A

increase with allergic reactions (hypersensitivities, inflammatory reactions)

18
Q

normal values of hemoglobin (Hgb)

A

Men : 13.5-17.5 g/dL

Women: 12-15.5 g/dL

19
Q

why can hemoglobin be low

A

bleeding, folate/B12 deficiencies, cancers, kidney & liver disease

20
Q

high hemoglobin b/c?

A

polycythemia, COPD, high altitude, heavy smoking

21
Q

What is hematocrit

A

percentage of blood that is made of packed red blood cells

22
Q

Interpret a hematocrit of 40%

A

indicates that there are 40mL of packed RBCs in 100 mL of blood

23
Q

normal values of hematocrit

A

Male: 41-50%
Female: 36-44%

24
Q

why may someone have low Hct

A

anemia, bleeding, bleeding disorders, FLUID IMBALANCES

25
why may someone have high Hct
polycythemia, COPD, dehydration, shock, congenital heart disease
26
what is a normal WBC total count
5,000-10,000/mm^3
27
what is increased WBC called
leukocytosis
28
what is decreased WBC called
leukopenia
29
what does total WBC count tell us
degree of immune response to something that is going on in your body
30
what is netropenia
low neutrophil count < 1000/mm^3 this patient is very sick
31
where are white blood cells made
bone marrow
32
Filgrastim
G-CSF MOA: promotes growth, differentiation, activation of cells that make granulocytes for cancer, chemo induced leukopenia, bone marrow transplant SE: bone pain, leukocytosis IV, SQ
33
Pegfilgrastim
MOA: increased production of neutrophils SE: bone pain Pegylated = delayed excretion by kidneys 1/2 life increase to 17 hours long acting