Male Reproductive Exam 4 Flashcards

(32 cards)

1
Q

risk factors for testicular cancer

A

family history
caucasian
cryptorchidism (empty scrotum)
HIV infection

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2
Q

what are germ cells

A

the sperm forming cells

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3
Q

what are the two types of germ cell tumors

A

seminomas and nonseminomas

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4
Q

Seminomas

A

arise from immature germ cells
slow growing, nonaggressive
easily cured with radiation

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5
Q

nonseminomas

A

arise from mature germ cells
more aggressive
usually treated with surgery

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6
Q

early clinical manifestations of germ cell tumors

A
enlargement of testicle 
painless mass notes
if discomfort present 
-ache in groin
-sensation of heaviness
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7
Q

late clinical manifestations of germ cell tumors

A
possible flank pain
based on metastatic spread: -cough 
-hemoptysis
-swelling of lower extremities
-back pain 
-dizziness
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8
Q

what is the prostate

A

gland surrounding the urethra

produces seminal fluids

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9
Q

what is Benign Prostatic Hyperplasia (BPH)

A

nonmalignant enlargement of prostate

increase in epithelial cells and increase in smooth muscle cells

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10
Q

what are risk factors for BPH

A
age 
family history 
race/ethnicity; 
-high - blacks
-low - asian
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11
Q

BPH cause/etiology

A

hormone imbalance

DHT accumulation - high levels of DHT activate growth factors

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12
Q

Clinical manifestations (S/S) for BPH

A

similar to UTI

frequency and urgency with urination, dribbling, reduction in force, increased urination time

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13
Q

BPH complications

A

obstruction - can obstruct urine from getting out of kidneys
UTI
renal problems

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14
Q

What are 5 alpha reductase inhibitors

A

finasteride and dutasteride

for BPH

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15
Q

MOA for finasteride and dutasteride

A

acts in reproduction tissue to inhibit 5 alpha DHT

blocks conversion of testosterone to DHT and decreases epithelial tissue in prostate

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16
Q

SE of finasteride and dutasteride

A

impotence (erectile disfunction)
decreased libido
gynecomastia - abnormal growth of breast tissue

17
Q

Nursing considerations for finasteride and dutasteride

A

pregnant nurses can not handle this drug

men can not give blood while talking the drug

18
Q

what are alpha1-adrenergic antagonists

A

tamsulosin

for BPH; dynamic obstruction of urethra

19
Q

MOA of tamsulosin

A

relaxes smooth muscle cells and selective for alpha receptors in the prostate

20
Q

SE of tamsulosin

A

well tolerated

abnormal ejaculation

21
Q

Prostate cancer risk factors

A

age
familial tendency
high fat diet

22
Q

prostate cancer in races

A

Highest - black/ african american

lowest - native american and asian

23
Q

what is erectile dysfunction

A

impotence; inability to achieve or sustain an erection sufficient for satisfactory sexual intercourse

24
Q

Primary ED

A

rare; life-long inability to have a normal erection;
severe psychiatric problems
early vascular trauma

25
secondary ED
most common | ED in someone with a history of normal erections
26
what is the physiology of a normal erection
sexual arousal --> increased parasympathetic nervous system and nitric oxide release --> activation of cGMP --> relaxation of arteries and smooth muscles --> increased inflow and reduced outflow --> engorgement and erection
27
what removes cGMP
PDE-5
28
what are PDE-5 inhibitors
sildenafil (Viagra) | for erectile dysfunction
29
MOA of sildenafil
inhibits PDE5, increases and preserves cGMP levels
30
SE of sildenafil
heart attack, flushing, dyspepsia
31
cautious with sildenafil
do not take if you are taking any nitrates - will cause significant decreased BP no more than once per day
32
what is priapism
erection is painful or lasts more than 4 hours