Blood Components and Derivatives part 2 Flashcards Preview

Fundamentals in Blood Bank > Blood Components and Derivatives part 2 > Flashcards

Flashcards in Blood Components and Derivatives part 2 Deck (42):
1

It is the component remaining after cryoprecipitate is prepared

Cryopoor plasma

2

Vol of Cryopoor plasma

200ml

3

Shelf Life of Cryopoor Plasma

same as FFP 1 year -18*C or below

4

Cryopoor Plasma has a minimal concentration of what Clotting factors

Fibrinogen , Factor VIII and VWF

5

Fxn/Uses of Cryopoor Plasma

Used in patients with hemolytic uremic syndrome , Thrombotic Thrombocytopenic Purpura

6

Volume of Cryoprecipitate

10-15ml

7

Shelf life of Cryoprecipitate

1 year @ -18*C below

8

Shelf life of Cryoprecipitate after thawing

6hrs

9

Cryoprecipitate used when there is congenital or acquired deficiencies of _______ and Factor ______

Fibrinogen and Factor XIII

10

Maybe benefecial in bleeding due to uremic platelet dysfunction not responding to desmopressin, estrogen

Cryoprecipitate

11

Uses of Cryoprecipitate

VWF , Hemophilia A when virus inactivated factor concentrates are not available
Deficiency in Factor 1 and 13

12

Volume of Factor VIII ( Lyophilized)

25 ml of sterile diluents for reconstitution

13

Shelf life of Factor V111 ( Lyophilized )

2years @ 2-8*C

14

Factor IX complex

Factor 2, 7, 9 and other proteins

15

Used to treat hemophilia B and patients with inhibitors to factor 8 and 9

Plasma derived factor 9

16

Antithrombin 3 concentrate are prepared from pooled human plasma by __________

Modified cold ethanol fractionation

17

In Antithrombin 3 concentrate treatment is for prophylaxis of thrombotic events in patient w/ congenital antithrombin deficiency . What are these congenital antithrombin defeciency

DIC , Heparin resistance , Sepsis , Deep Vein thrombosis , Pulmonary Embolism

18

Antithrombin 3 concentrate volume

Volume per manufacturers direction

19

What is the purpose of Solvent/Detergent treatment to plasma

To deactivate lipid enveloped viruses ( HIV , HCV)

20

Vol. of S/D treated plasma

200 ml

21

Shelf life of S/D treated plasma

1 year @-18 *C

22

True or False . S/D treated plasma has minimal content of Low Molecular Weight VWF

False S/D treated plasma has minimal content of High Molecular Weight VWF

23

Plasma as in FFP , stored and released for use after donor has been retested negative for viral markers after days or more , allowing for window period infections to seroconvert

Donor Retested Frozen Plasma

24

In Donor Restested Frozen Plasma .donor has been retested negative for viral markers after_____ days or more , allowing for window period infections to seroconvert

112 days

25

Volume of Donor Retested Frozen Plasma

200-260 ml

26

Difference between Donor Retested Frozen Plasma and FFP

Donor Retested Frozen Plasma has lower risks of viral transmission than FFP

27

Albumin Shelf life

5 years @ 2-10*C

28

Volume of Albumin

250-500ml

29

How many % of albumin and globulin are there in Plasma Protein Fraction

83 % Albumin , 17 % globulin

30

In Plasma Protein Fraction Hypotension may occur when givent at males over __ml/min

10 ml/min

31

Plasma Protein Fraction shelf life

3 years below 30*C

32

Plasma Protein Fraction volume

250-500ml

33

Albumin contraindications

Dehydrated Patients

34

Used in Primary humoral immunodeficiency, ITP , Bone marrow transplant and pediatric HIV infection

Immunoglobulin Intravenous

35

Immunoglobulin Intravenous volume

10-200ml

36

Shelf life of Immunoglobulin Intravenous

3 years @ 2-8*C

37

Immunoglobulin Intravenous gained acceptance in the treatment of ______

Guillain Barre's Syndrome

38

Immunoglobulin Intravenous antibodies

Mostly IgG , Traces of IgA and IgM

39

Uses of Rh Ig

Prevents Rh alloimmunization of Rh neg. individual exposed to the D antigen
Used to prevent HDN

40

IgG anti-Rho full dose is ___µg , minidose is ____µg

300µg and 50µg

41

Volume of Rh Ig

1ml

42

Shelf life of Rh Ig

1/2 years @ 2-8*C