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Fundamentals in Blood Bank > Blood Components and Deriviatives > Flashcards

Flashcards in Blood Components and Deriviatives Deck (50):
1

2 Fxn of Whole Blood

Replacement of O2 carrying capacity
Maintainance of Intravascular Vol.

2

Fxn of Packed Red Blood Cell

To increase O2 carrying capacity of blood in patient with Acute Chronic Anemia who are symptomatic or at High risk for end organ damage

3

Volume of Packed Red Blood Cell

260 ml

4

A product in which all of the red cells and most of the plasma from the original unit remain

Whole blood

5

Volume of Whole Blood

540 ml

6

Packed RBC maybe prepared from whole blood by _______ or by ________

Overnight sedimentation or by Centrifugation using Heavy Spin

7

Whole Blood Shell life for CPA-1

35 Days at 1-6*C

8

Whole Blood Shell life for CPD

21 Days at 1-6*C

9

In packed RBC what are the two symptoms of Acute Chronic Anemia mentioned

Syncope and Dyspnea

10

Give example in Packed RBC for High Risk for end organ damage

Subcritical Coronary Atherosclerosis

11

How many ml of Additive solution is added in the RBC

100ml

12

Volume of RBC added with Additive solution

340ml

13

3 Fxn/Uses of transfused Washed RBC

1.Prevention of recurrent or severe allergic reactions
2.Neonatal intrauterine transfusion
3.Prevention of anaphylactic reaction in IgA deficient patients

14

Washed RBC volume

180ml

15

Wahsed RBC Shelf Life

24hrs at 1-6*C

16

3 Fxn/Uses of Frozen Deglyceralyzed RBC

1.Long Term preservation of RBC units with rare phenotype or autologous RBC units
2.Alternative to CMV seronegative unit emergencies
3.Decrease febrile transfusion reaction

17

Removes >90% of WBC

Frozen Deglyceralized RBC

18

Shelf life of Frozen Deglyceralized RBC

10 years at -65 to - 200 *C

19

Shelf life of Frozen Deglyceralized RBC after washing

24 hrs at 1-6*C

20

Volume of Frozen Deglyceralized RBC

250ml

21

4 Fxn/uses Leukocyte Reduced RBC

1.Decreased the risk of alloimmunization to HLA antigens on leukocyte
2. Decrease Febrile Non-Hemolytic transfusion reaction
3. Reduce the risk of CMV infection
4.Decrease immunomodulation and may decrease the risk of prior transmission in B lymphocytes

22

A product in which the leukocyte is reduce in the blood to prevent alloimmunization to HLA antigens

Leukocyte Reduce RBC

23

Volume of Leukocyte Reduce RBC

Similar to Original Unit

24

Shelf life of Leukocyte Reduce RBC

Similar to Original Unit if Closed system is used

25

Two RBC are divided into two seperate RBC units of equal volume

Two/Double Unit RBC Apheresis

26

Volume of Two Unit RBC apheresis

320ml

27

True or False . Two Unit RBC apheresis is similar to Packed RBC

True

28

Shelf life of Two Unit RBC

1 yr at 1-6*C

29

Use if Bleeding due to quantitative and qualitative platelet disorders

Random Donor Platelet Concentrate

30

Volume of Random Donor Platelet concentrate

50-70 ml

31

Random Donor Platelet concentrate is used in Prophylaxis in __________ patients . Give also the value

Severe Thrombocytopenic Patients ( 5000-10 000/UL)

32

Shelf life of Random Donor Platelet concentrate

5 days with constant gentle agitation

33

Shelf life of Random Donor Platelet concentrate after pooling platelets pheresis

4 hrs

34

Volume of Single Platelet

200-400 ml

35

In Single Platelet what is the volume of plasma to maintain pH.

250ml to achieve pH above 6.2

36

pH of Single Platelet

pH of above 6.2

37

True or False . In Single Platelet indication is not similar to random donor platelets

False

38

Shelf life of Single Platetlet

5 days @ 20-24*C with constant gentle agitation

39

It is used when additional prevention of alloimmunization to HLA antigens or reduction of CMV infection risk is desired

Leukocyte Reduced Platelets

40

Leukocyte Reduced Platelets indications

Per random donor or pheresis platelets

41

In Leukocyte Reduced Platelets it is done immediately before transfusion ( 3 log Filtration)

Bedside filtration

42

Volume of Granulocyte Pheresis

200-300ml

43

Granulocyte Pheresis shelf life

24 hrs @20-24*C

44

An apheresis product or component with only granulocytes and other WBC

Granulocytes pheresis

45

It is used when specific coagulation factor deficiency where coagulation factors are not available

FFP Fresh Frozen Plasma

46

Granulocytopenia with persistent fever or infection. Give na value of Granulocytes

47

Fresh frozen plasma contains

All coagulation factors , Complement other plasma proteins

48

Volume of Plasma Proteins

200-260 ml

49

Shelf life of Plasma Proteins

1 year @ -18*C

50

It is used when there is bleeding due to multiple coagulation factor Deficiency

Plasma Proteins