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Fundamentals in Blood Bank > Relationship Testing > Flashcards

Flashcards in Relationship Testing Deck (22):
1

Described the charged polymorphism of haptoglobin

1955 Smithies

2

Demonstrate that the ABO blood group frequency distribution in Austria

Bernstein 1924

3

We're officially recognize by the FBI as the core loci to be used to create query the database of convicted offender

13core STR loci plus amelogenin

4

Amelogenin are used by the FBI for

Sex determination

5

A group of genetic system wherein the detection of the polymorphisms where all dependent on a complex biochemical expression of the original gene

Classic system

6

Refers to polymorphisms in DNA that can be revealed by restriction enzyme digestion because of nucleotide sequence differences that either create or destroy restriction sites

Restricted fragment length polymorphisms

7

Classic genetic systems use in parentage testing

RBC antigen
RBC enzyme and serum proteins
Immunoglobulin Allotypes
HLA

8

Are defined as the length of DNA fragments in kilobases estimated through comparison to a sizing ladder consisting of DNA fragments of known size

Phenotype

9

Indirect exclusion is also referred as ?

Apparent opposite homozygosity

10

The limit of resolution is referred to as

Delta

11

In DNA: RFLP variability is referred as

Sigma

12

The range of matching allele sizes is called

bin

13

2 Most common restricted enzyme used in USA

Hae III and Pst I

14

Restricted enzyme use in Europe

Hint I

15

Name of the bacteria wherein Hae III enzyme is restricted

Haemophilus aegyptus

16

Paternity index is also known as

System index

17

Compares two mutually exclusive hypothesis that are expressed as a likelihood ratio

Paternity index

18

Is the probability of excluding a false,y accused man giving the phenotype of the mother and child

Probability exclusion

19

Is a restatement of the weight of the evidence for parentage expressed in parentage form

Probability paternity

20

Give the formula probability paternity

( [PI) ( prior for ) ] / [ ( PI ) ( prior for ) + prior against

21

Refers to the testing of genetic markers that are inherited to confirm or refute a biological relationship

Relationship testing or parentage testing

22

Classic Genitic System Used in Parentage Testing using RBC Enzymes and Serum Proteins

H-E-P-A - G