Blue 2-2 Flashcards

(30 cards)

1
Q

What is the criteria for migraine with aura? What is the risk?

A

Criteria - 2 typical attacks of migraine with aura symptoms

Increased risk of ischaemic stroke and MI

Unilateral pain lasting 4-72hours with N/V, photophobia/phonophobia
Female 3:1

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2
Q

What is Riddoch penomenon

A

Preserved awareness of moving but not stationary stimuli

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3
Q

What is Pulfrich phenomenon

A

Patient see targets moving towards them when the targets are moving laterally
(optic nerve diseases)

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4
Q

What is Anton syndrome

A

Cortical blindness who deny their blindness

Due to bilateral retrochiasmal visual pathway diseases such as bilateral occipital lobe infarction.

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5
Q

What is CedIak hIgashI syndrome

A

Autosomal recessive
Recurrent severe pyogenic Infections
Progressive neuro abnormality
Mucosal disease
Albinism

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6
Q

What is Griscelli sydnrome

A

Neurological deficit with or without immunological impairment
Lack of giant intracellular granules
Albinism

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7
Q

What is Hermansky Pudlak syndrome

A

Platelet deficiency resulting in bleeding
Pulmonary disease
Granulomatous colitis
Albinism

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8
Q

Waardenburg syndrom

A

Iris heterochromia
Broad nasal root
White forelock

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9
Q

What are ocular abnormlaitties in congenital zika syndrome? How transmitted?

A

70% of patients will have ocular abnormlaiteis

Posterior segment abnormaliteis most common
RPE loss
CHoroidal inflammatory infiltrates
Chorioreitnal atrophy
REtinal haem

Iris coloboma, glaucoma, cataract

TRansmitted via mosquito from Aedes genus

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10
Q

What is treatment for prolactimona

A

Bromocriptine dopamine agonist

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11
Q

What enzyme is reduced in albinism

A

Tyrosinase - responsible for melanin synthesis

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12
Q

What conditions cause saddle nose deformity

A

TRauma
Surgery
Granulomatosis and polyangiitis (cANCA)
Relapsing polychondritis
Sarcoidosis
Crohn’s
Syphilis
Leprosy
Septal abscesses

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13
Q

Treatment for fluorescein anaphylaxis

A

0.5mg 1:1000 IM adrenaline

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14
Q

What is hemifaical spasm

A

Sporadic/AD
Female
40-60

Involuntary synchronous tonic and/or clonic contraction of facial msucles

Caused by dysfunctional facial nerve
Result of anomalous vascular compression of the facial nerve

  • AICA and PICA are most common compressing vessels
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15
Q

What is Purtscher retinopathy

A

Traumatic casue (indirect non ocular)

Cotton wool spots
Retinal haemorrhages
Optic disc oedema
Purtscher flecken (areas of polygonal retinal whitening)
Findings usually peripapillary

Purtscher like retinoapthy (not associated with trauma)

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16
Q

What is Budd Chiari syndrome?

A

Thrombosis of hepatic portal vein

17
Q

What is Arnold Chiari syndrom

A

Anatomical anomaly at foramen magnum predisposing to cerebellar tonsillar descent and brain stem compression

18
Q

What can BEhcet’s disease cause resulting in bilateral 6th palsy and papilloedema

A

Dural venous sinus thrombosis

19
Q

What is erythema chronicum migrans? What causes it?

A

Target appearance with erythema and inducation at centre

Borrelia burgdoferi - tick bit - lume disease

20
Q

What casues cat scratch disease?

A

Bartonella henselae

Oculoglandular syndrome
KEratitis
NEuroretinitis
Uveitis

21
Q

When to do DEXA scan

A

Continuous oral corticosteroid for >3 months

22
Q

Bone protection in glucocorticoid useH

A

Women and men >70 with previous fragility fracture taking high dose >7.5mg OD)
Start at onset of glucocorticoid therapy

23
Q

What are scores of DEXA scan

A

Normal 0 to -1
Osteopenia -1 to -2.5
Osteoporosis -2.6 or less

24
Q

Hba1c target and good level

A

<48 on diet/single oral drug therapy

<53 in pts with drug hypoglycaemia and in patients with hba1c > 58

25
What is the treatment for CMV reintitis
intravitreal foscarnet and oral valganciclovir
26
What are risks of valganciclovir
Myelotoxic and nephrotoxic
27
What are features of bilateral superior oblique palsy
CRAVE Chin down posture Reversing hyperdeviation - left gaze (R/L) and right gave (L/R) Adduction failure in depression V pattern Excyclotorsion < 10 degrees
28
BEst outcome gene mutation in LHON?
14484 (11778 - poor outcome)
29
What is palinopsia
Persistence or recurrence of visual images after removal of initial stimulus May be caused by disease affecting parieto occipital pathway or topiramate, risperidone, mirtazapine, acetazolamide TReated with carbemazepine
30
What is Parinaud dorsal midbraine syndrome?
Damage to vertical gaze centre at rostral interstitial nucleus of MLF DULL PC Downward gaze in primary Upward gaze palsy Light near dissociation - impaired pupillary light reflex but preserved accommodation. Lid reatraction (collier's sign) Papilloedema Convergence retraction nystagmus Saccadic movement affected first, then smooth pursuit and vestibulo ocular reflex