Bones, Joints and Soft Tissue Flashcards
(27 cards)
Most common skeletal dysplasia
Achodroplasia
Most common lethal form of dwarfism
Thantophoric Dysplasia
Most common inherited disorder of connective tissue
Osteogenesis Imperfecta
Most lethal type of OI
Type II
Marble bone disease
Osteopetrosis
First disorder to be treated with HSC transplantation
Osteopetrosis
Absence of medullary canal + Erlenmeyer flask deformity
Osteopetrosis
“jigsaw puzzle” mosaic pattern of lamellar bone with cement lines seen in
Paget disease (Osteitis deformans)
Rail-road track appearance
Dissecting osteitis in hyperparathyroidism
Legg-Calve-Perthes Disease associated with
Osteonecrosis
Most common benign bone tumor
Osteochondroma
Olier and Maffucci syndrome associated with
Chondroma
Second most common bone sarcoma in children
Ewing Sarcoma
Mutation in Ewing Sarcoma
t (11,22)
small round blue cells, Homer-wright rosettes
Ewing sarcoma
Curvilinear trabeculae of woven bone without osteoblastic rimming- “Chinese characters”
Fibrous dysplasia
Most common skeletal malignancy
Metastases
Bouchard vs Heberden nodes
Bouchard: PIP (BP)
Heberden: DIP (HD)
Pannus and osseous ankylosis seen in
Rheumatoid arthritis
Triad of Felty syndrome
splenomegaly, neutropenia, RA
Bamboo stick appearance of spine
Ankylosing spondylitis
Triad of Reiter Syndrome
Arthritis, nongonococcal urethritis/cervicitis, conjunctivitis
Pencil in a cup deformity
Psoriatic arthritis
Monosodium urate, neg bifringent
Gout
