Liver and Gallbladder

Question 1

Lab tests to measure hepatocyte integrity

Answer 1

AST (SGOT)
ALT (SGPT)
LDH

*OSPL

Question 2

Lab tests to measure biliary excretory function

Answer 2

Bilirubin (total direct and indirect)
Alkaline phosphatase
GGT

Question 3

Lab tests to measure hepatocyte synthetic function

Answer 3

Albumin
PT, aPTT
Ammonia

Question 4

Mnemonics for Acute Liver Causes

Answer 4

ABCDEF

A-acetaminophen, hep A, autoimmune hepa
B-hepa B
C-hepa-C, cryptogenic
D-drugs/toxin, hep D
E-hep E, esoteric causes (Budd-Chiari syndrome)
F-fatty change of the micro-vesicular type (FLP, valproate, tetracycline, Reye syndrome)

Question 5

Mallory-Denk bodies are clumped, amorphous, eosiniphilic material associated with

Answer 5

Alcoholic Steatohepatitis

Question 6

Perisinusoidal chicken-wire fence patterns of fibrosis is associated with

Answer 6

Steatofibrosis

Question 7

Most common metabolic liver disease

Answer 7

NAFLD

Question 8

Triad of Hemochromatosis

Answer 8

1. Micronodular cirrhosis
2. DM
3. Abnormal/skin pigmentation

Question 9

Most commonly diagnosed inherited hepatic DO in infants and children

Answer 9

a-1 antitrypsin deficiency

Question 10

Inherited causes of Indirect hyperbilirubinemia

Answer 10

1. Crigler-Naijar I, II

2. Gilbert Syndrome

Question 11

Inherited causes of Direct hyperbilirubinemia

Answer 11

1. Dubin-Johnson

2. Rotor Syndrome

Question 12

Florid duct lesion associated with

Answer 12

Primary Biliary Cirrhosis

Question 13

Triad of choledochal cysts

Answer 13

1. pain
2. jaundice
3. abdominal mass

Question 14

Cystic dilatation of intrahepatic ducts associated with PBC

Answer 14

Caroli disease

Question 15

Most common benign liver tumor

Answer 15

Cavernous Hemangioma

Question 16

Most common liver tumor of early childhood

Answer 16

Hepatoblastoma

Question 17

Most common tumor involving the liver

Answer 17

Metastases

Question 18

Most common primary malignant tumor

Answer 18

HCC

Question 19

2nd most common primary malignant tumor

Answer 19

CholangioCA

Question 20

Most common location of CholangioCA

Answer 20

perihilar (Klatskin tumor)

Question 21

Most common billiary tract disease

Answer 21

Cholelithiasis

Question 22

Bouveret syndrome (gallstone ileus) is associated with

Answer 22

Cholelithiasis