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06_Pathology > Diseases of the Immune System > Flashcards

Diseases of the Immune System Flashcards

(7 cards)

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1
Q

complement activated in opsonization and phagocytosis

A

C3b

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2
Q

complement activated in inflammation

A

C3a and C5a

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3
Q

secretes IFN-gamma which activates macrophages to secrete cytokines

A

TH1

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4
Q

produces IL-17 and other cytokines for leukocyte recruitment

A

TH17

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5
Q

direct killing by perforins and granzymes in lysosome-like granules

A

CD-8+

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6
Q

MC autoantibody produced in SLE; best screening test

A

ANA

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7
Q

autoantibody specific for SLE

A

anti-Sm and anti-dsDNA

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06_Pathology (20 decks)

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