CNS Flashcards

(26 cards)

1
Q

Sum of CSF, brain tissue and blood is constant

A

Monroe-Kellie doctrine

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2
Q

Cowdry Type A inclusion bodies

A

HSV

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3
Q

Periventricular Necrosis and calcification

A

CMV

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4
Q

Neuronophagia of the anterior-horn motor neurons

A

Poliomyelitis

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5
Q

Microglial nodules

A

HIV

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6
Q

Central foci of necrosis, ring-enhancing lesions

A

Toxoplasma

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7
Q

Soap bubbles appearance

A

Cryptococcus

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8
Q

Most common demyelinating DO

A

Multiple sclerosis

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9
Q

Common initial manifestation of multiple sclerosis

A

unilateral involvement of optic nerve

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10
Q

Charcot triad of multiple sclerosis:

A

nystagmus, intention tremor, scanning speech

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11
Q

CSF finding: mod pleocytosis, mildly elevated protein, inc IgG (oligoclonal)

A

Multiple sclerosis

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12
Q

AB, Tau

A

Alzheimer dse

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13
Q

Tau, a-synuclein

A

Parkinson dse

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14
Q

polyglutamine aggregates

A

Huntington dse

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15
Q

TPD-43, FUS

A

ALS

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16
Q

GAA Trinucleotide repeat expansion

A

Friedrich ataxia

17
Q

Mnemonics for Wernicke Encephalopathy

A

ACO

ataxia, confusion, ophthalmoplegia

18
Q

Mnemonics: Korsakoff syndrome

A

CHO

confabulations, hallucinations, amnesia

19
Q

Most common brain tumor in children

A

infratentorial

20
Q

Most common brain tumor in adults

A

supratentorial

21
Q

Most common brain tumor

22
Q

Most common primary brain tumor

23
Q

Location of astrocytoma in children/adults

A

Children: cerebellum
Adults: cerebral cortex

24
Q

Locatioon of ependymoma in 1st two decades/adults

A

1st two decades: near 4th ventricle

Adults: spinal cord

25
1p19q co-deletion
Oligodendrioglioma
26
Most common poorly differentiated brain tumor
Medulloblastoma