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Flashcards in brain tumor pathology Deck (20):
1

most common primary brain tumor

glioblastoma multiforme

2

most common locations that metastasize to brain (6)

lung > breast >GU> osteosarcoma> melanoma> GI

3

HA, vomiting, papilledema, ocular palsies, altered LOC, back pain

increased ICP

4

what to administer to lower ICP

mannitol

5

location: adult tumors are ____tentorial vs kid tumors are ___tentorial

supra; infra

6

a tumor of the posterior fossa is likely to be in kid or adult?

kid

7

Malignant, prominent necrosis and haemorrhage, crosses corpus callosum, hyperchromatism, pleomorphism, GFAP+, pseudopalisading

glioblastoma multiforme

8

Tight whorling appearance, psammoma bodies

meningioma

9

arises from arachnoid cells, benign, can present with seizures

meningioma

10

Bubbly cytoplasm in stromal cells, benign

hemangioblastoma

11

hemangioblastoma most often occurs in_____

cerebellum

12

which brain tumor can produce EPO

hemangioblastoma

13

patient presents with retinal angioma, then later a tumor in cerebellum is found

hemangioblastoma secondary to VHL

14

Cerebellopontine angle; S100+, CN VIII

schwannoma

15

small round nuclei with perinuclear halo; fried eggs cells and chicken wire vasculature

oligodendroglioma

16

a thick, elongated, worm-like or "corkscrew" eosinophilic (pink) bundle on H&E staining

rosenthal fiber

17

rosenthal fiber, cystic lesion with a mural nodule, GFAP+, child

pilocytic astrocytoma

18

which tumor can send drop metastases to SC

medulloblastoma

19

hydrocephalus, homer wright rosettes, neuroectoderm origin

medulloblastoma

20

Perivascular pseudorosette

Ependymoma