Breast Histology Flashcards

(31 cards)

1
Q

What layer of the skin is the breast found within?

A

subcutaneous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of glands are found within the breast?

A

compound tubulo-acinar gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is found adjacent to the secretory lobules of the breast?

A

dense fibrous tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What surrounds the dense fibrous tissue of the breast?

A

adipose tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the suspensory ligaments of the breast?

A

large condensations of fibrous connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What do the suspensory ligaments attach between?

A

dermis of the skin to the deep fascai overlying the muscles of the anterior chest wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What area of the breast are suspensory ligaments most ponounced?

A

upper breast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the basic functional secretory unit of the breast?

A

terminal duct lobular unit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where do the terminal ductules drain into?

A

intralobular collecting duct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does the intralobular collecting duct lead into?

A

lactiferous duct for that lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the expanded duct region near the nipple known as?

A

lactiferous sinus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What surrounds the acini wtihin the lobule?

A

loose connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the function of loose connective tissue within the lobules of the breast?

A

allow for rapid expansion during pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What cell type surrounds the secretory cells of the acinus?

A

myoepithelial cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What secretory epithelia is found within the lobule?

A

varies from cuboidal to columnar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What epithelium is found within the larger ducts eg lactiferous duct?

A

varies from thin stratified squamous to stratified cuboidal

17
Q

What epithelium covers the nipple?

A

thin, highly pigmented keratinised stratified squamous epithelium

18
Q

What makes up the cord of hte nipple?

A

dense irregular connective tissue mixed with smooth muscle

19
Q

what is the function of a lactiferous duct?

A

serves one lobe fo the breast

20
Q

What lines the lactiferous ducts as it approaches the surface?

A

stratified squamous epithelium

21
Q

What is different about the sebaceous glands of the nipple?

A

end directly on the skin instead of on a hair follicle

22
Q

What happens to the mammary glands during the luteal phase of htem menstrual cycle?

A

epithelial cells increased in heighgt; lumen of ducts increases and small amounts of secretions appear in the ducts

23
Q

What changes are seen to the breast during the first trimester of pregnancy?

A

elongation and branching of the smaller ducts; proliferation of the epithelial cells of the glands and myoepithelial cells

24
Q

What changes are seen in the breast in the second trimester?

A

glandular tissue continues developing; differentiation of secretory alveoli; plasma ells and lymphcytes infiltrates connective tissue

25
What changes are seen in the breast in the third trimester?
secretory alveoli continue to mature with development of extensive rER
26
What is the function of oestrogen and progesterone on the mammary gland during pregnancy?
stimulate proliferation of secretory tissue and fibro-fatty tissue becomes sparse
27
What substance is secreted via apocrine secretion?
lipids
28
What substance is secreted via merocrine secretion (exocytosis)?
protein
29
What is apocrine secretion?
lipid droplets are secreted surrounded by membrane
30
What is merocrine secretion?
via vesicles which merge with apical membrane to release contents into ducts
31
What changes happen to the breast following menopause?
secretory cells of TDLUs degenerate leaving only ducts; fewer fibroblasts and reduced collagen and elastic fibres