Flashcards in C- Hemodynamics & Vasculature Deck (28):

1

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________ is Highest in aorta.

###
Pressure

Pressure decreases through system, especially in resistance vessels (sm arteries & arterioles)

2

## Pressure is_______ in capillaries and venous system

### low

3

##
Total blood volume ~ 5 L

Largest volume in _______(“capacitance vessels”)

### veins

4

##
Q = DP/R

this represents?

###
Q = DP/R

Pressure differences (ΔP) drive blood flow (Q). Vascular resistance (R) opposes blood flow.

5

##
volume per unit time (ml/min)

CONSTANT through system (since closed loop)

CARDIAC OUTPUT (CO) = Total flow in the cardiovascular system

###
Flow (Q)

6

##
distance per unit time (cm/sec)

v=Q/A (flow/cross sectional area)

Velocity highest in aorta (lowest total cross-sectional area), lowest in capillaries (greatest cross-sectional area).

###
Velocity (v)

7

##
CO = (Pa-Pv)/TPR

###
Cardiac Output

Pa = mean arterial blood pressure

Pv = venous blood pressure

TPR = total peripheral resistance

Variation of flow equation: Q=DP/R

8

##
_______ is the volume of blood pumped per minute by the heart (~5 L/min at rest)

###
Cardiac Output (CO)

CO = (Pa-Pv)/TPR

9

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___________ corresponds to the total flow in cardiovascular system

###
Cardiac Output

CO = (Pa-Pv)/TPR

10

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Flow is proportional to 4th power of radius. Thus ___________ is the biggest determinant of flow.

### radius of vessel

11

##
Flow is proportional to ____________. Thus radius of vessel is the biggest determinant of flow.

### 4th power of radius

12

## resistance of a parallel network is ________ than the resistance of any single vessel

###
lower

*Changing the resistance of a single vessel has little effect on the system

13

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Total resistance of a series of vessels is _________ than the resistance of any individual vessel

###
higher

*Resistances in series are additive

14

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(flow)

Most efficient

Velocity fastest in center, zero at edge

Flow equation assumes this flow. Not true in CV system

###
Laminar flow

15

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(flow)

Irregular, with eddies and vortices

Less efficient – requires more pressure to achieve same velocity

Promoted by large diameter, high velocity, low viscosity, changes in diameter, and irregularities on walls

###
Turbulent flow

*Turbulent flow produces shearing forces that can damage vascular endothelium

16

##
Heartbeat produces _____ flow in aorta, but _____ flow requires more work. dampened in arterial system.

### pulsatile

17

##
FLOW IS __________IN CAPILLARIES

### CONTINUOUS

18

##
Systolic pressure =

### peak aortic pressure

19

##
Diastolic pressure =

### minimum aortic pressure

20

## Blood pressure is expressed as

### systolic/diastolic = ex 120/80 mmHg

21

##
Vessels lose compliance with age =

###
arteriosclerosis

Compliance represents the elastic properties of vessels (or chambers)

22

## arteriosclerosis results in

###
Older people have higher systolic pressure and higher pulse pressure than younger people

23

##
Tension in wall increases as pressure and radius increase.

Walls of larger vessels subject to greater tension.

________ increases stress on walls of vessels and chambers.

### Hypertension

24

## Law of LaPlace:

### Relationship between wall tension & transmural pressure

25

##
Cardiovascular Transport Two processes

###
Bulk transport

Transcapillary transport

26

##
refers to movement of a substance through the cardiovascular system from point A to point B.

### Bulk transport

27

##
describes the movement of a substance between capillaries and tissue

### Transcapillary transport

28