Calcium Channel Blockers Flashcards
1
Q
name three calcium channel blockers
A
amlodipine
diltiazem
verapamil
2
Q
what do they target?
A
L type calcium channels
3
Q
agonist or antagonist ?
A
antagonist
4
Q
how do they work?
A
blocks entry of Ca2+ therefore reducing [Ca2+]
5
Q
what is their overall effect?
A
vasodilation and/or negative inotropic effects on the heart
6
Q
what are they used for?
A
hypertension (-dipines)
supraventricular arrhythmias (verapamil)
angina
7
Q
adverse effects?
A
headache flushing tachycardia peripheral oedema heart block
8
Q
prescribing advice
A
NOT with myocardial depression, impaired conduction
NOT with digoxin/ B-blockers
