Carbonic anhydrase inhibitors

Question 1

name a carbonic anhydrase inhibitor ?

Answer 1

acetazolamide

Question 2

what do they target?

Answer 2

carbonic anhydrase enzyme

Question 3

agonist/ antagonist?

Answer 3

inhibitor

Question 4

what do they do?

Answer 4

reduce formation of H2CO3 in PCT epithelial cells
decrease H+ secretion
reduces Na+, K+, HCO3- reabsorption

causes sodium diuresis and bicarbonate depletion

Question 5

used for?

Answer 5

altitude sickness

glaucoma

Question 6

adverse effects?

Answer 6

renal stone formation 
decrease :
Na
K
Ca
pH