Cysteinyl leukotriene antagonists Flashcards
1
Q
what do cysteinyl leukotriene antagonists end in?
A
lukast
2
Q
name two examples of cysteinyl leukotriene antagonists
A
montelukast
zafirlukast
3
Q
what do they target?
A
CysLT1 receptor
4
Q
agonist/antagonist?
A
antagonist
5
Q
how do they work?
A
decreases leukotriene activity
prevents inflammatory response and smooth muscle proliferation
6
Q
what are they used for?
A
prophylaxis for exercise and antigen induced asthma
7
Q
adverse effects ?
A
cough
paradoxical bronchospasm
