Cancer Flashcards

(45 cards)

1
Q

What is the second leading cause of death in North America?

A

Cancer

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2
Q

Why is early detection of cancer problematic?

A

It can spread rapidly

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3
Q

Why is CAUTION not particularly helpful?

A

It’s very vague

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4
Q

CAUTION stands for the following:

Change in bowel or bladder habits
A sore that does not heal
Unusual bleeding or discharge
Thickening or lump in the breast or elsewhere
Indigestion or difficulty in swallowing
Obvious change in a wart or mole
Nagging cough or hoarseness
A

CAUTION stands for the following:

Change in bowel or bladder habits
A sore that does not heal
Unusual bleeding or discharge
Thickening or lump in the breast or elsewhere
Indigestion or difficulty in swallowing
Obvious change in a wart or mole
Nagging cough or hoarseness
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5
Q

What occurs when normal body cells lose the ability to control their division?

A

Cancer

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6
Q

What are the normal processes in our body in place to prevent uncontrolled cell division in the body?

A

Apoptosis

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7
Q

How do DNA mutations in cells usually prevent cancer cells from dividing?

A

They trigger certain proteins to be produced that stop the cell from diving and often kills the cell

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8
Q

Why is it difficult for our immune system to recognize and kill cancer cells?

A

They are their own body cells

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9
Q

Is it true that everyone has cancer?

A

Yes

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10
Q

According to the conventional wisdom, what is the main/core cause of cancer?

A

Random genetic mutations

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11
Q

Which part of the cell is damaged that leads to cancer?

A

The DNA

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12
Q

What are 3 potential causes of damage to DNA?

A
  1. Uncontrolled Cell Replication
  2. Lack of Apoptotic Signaling
  3. Increased Invasive and Metastatic Properties
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13
Q

What percent of cancers are thought to be attributed to genetic predisposition?

A

60%

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14
Q

What percent of cancers are thought to be due to environmental causes?

A

40%

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15
Q

What are 3 environmental causes of cancer?

A
  1. Toxins
  2. Low antioxidant intake
  3. Poor diet
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16
Q

What are masses of cells that can be cancerous or noncancerous?

A

A Tumor

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17
Q

What are noncancerous tumors that do not spread?

A

Benign

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18
Q

What is property of spreading locally and to distant sites?

A

Malignant

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19
Q

What is the spreading of disease from the site of the original tumor to parts of body that are remote?

20
Q

What are the 3 main ways that we treat cancer?

A

Surgery, Chemotherapy, and Radiation

21
Q

What characteristic of cancer cells is different from most normal cells that is used to target cancer cells?

A

Cancer cells rapidly divide while most normal cells don’t

22
Q

What uses drugs that interfere with a cell’s ability to divide?

23
Q

What are the 3 common mechanisms of chemotherapy

A

Impair DNA synthesis, trigger cell death, and stop growth of new blood vessels

24
Q

What is a side effects associated with Chemotherapy?

A

The treatments targets important cells for your body that also rapidly divide

25
What important cells does Chemotherapy also target?
Immune cells and intestine cells
26
What are 5 of the symptoms associated with cancer?
Hair loss, nausea, vomiting, chronic infections, skin problems
27
Are the symptoms associated with cancer caused by the cancer or the cancer treatment?
The cancer treatment
28
What uses high-energy radiation to damage and kill cancer cells?
Radiation
29
What is a side effect of radiation treatment?
It can cause cancer
30
How are free radicals thought to contribute to cancer susceptibility?
They damage DNA
31
How do dietary antioxidants protect against cancer?
They neutralize free radicals
32
What property is common to all cancer types and cells?
Metabolic Dysfunction
33
Are DNA mutations the same in all types of cancer?
No
34
Are DNA mutations the same in one cancer in one patient?
No
35
How was it shown that cancer does not arise from DNA?
He took a normal cell and put cancerous DNA in it and let it divide and it produced normal cells
36
How was it shown that cancer does not arise from the nucleus?
He took a cancerous cell and put a normal nucleus in it and let it divide and it became a tumorous cell
37
Which cellular organelle was found to be the real source of cancer?
The cell mitochondria
38
What cellular function does the organelle of cancer perform?
It is where most energy metabolism comes from
39
Which macronutrients can normal cells use for energy that cancer cells cannot?
The Microconidia
40
Which macronutrient are cancer cells dependent on for energy?
Glucose
41
What does cancer cells being depended on glucose or energy mean in terms of therapies for cancer?
It might be possible to “starve” cancer by not giving it glucose
42
How does the metabolism of a cancer cell differ from the metabolism of a normal cell?
Cancer cells have a damaged microconidia and it produces a lot of lactate
43
What diet should you go on to "starve" cancer?
Ketogenic Diet
44
Can cancer cells use fatty acids or ketone bodies for energy?
No
45
Does lactate make a lot of energy or very little energy?
Very little energy