Carbapenems Flashcards
1
Q
Carbapenems Description
A
Bicyclical beta-lactams with a common carbapenem nucleus; most broad-spectrum agents available.
2
Q
Carbapenem Distribution
A
widely distributed into most tissues, are minimally bound to plasma proteins
3
Q
Carbapenems Half life
A
1 hour
4
Q
Carbapenems Elimination
A
are primarily eliminated by urinary excretion
5
Q
Carbapenems Mechanism of Action
A
bind to the PBPs on cell wall and interfere with bacterial cell wall synthesis.
6
Q
Carbapenems Clinical Uses
A
treating polymicrobial infections
7
Q
Carbapenems Side effects
A
neurotoxicity GI side effects reported.
