Glycopeptides Flashcards
1
Q
Glycopeptides Most common example
A
Vancomycin: originally known as “Mississippi Mud” for impurities; important antibiotic has been used since 1980s; drug of choice for methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive infections.
2
Q
Glycopeptides New additions (vancins)
A
Dalbavancin
oritavancin
telavancin
have a narrow spectrum of activity directed toward gram-positive organisms.
3
Q
Glycopeptides Peaks and Troughs
A
Serum drug monitoring is used for vancomycin in patients with unpredictable kidney function or severe infections or those receiving therapy for more than 3 to 5 days.
4
Q
Glycopeptides Side effects (vancomycin)
A
Red man syndrome from histamine release
Nephro and oto toxic possible
